Protein Alignment ey and Pax5

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_032808.1
• Gene: Pax5 / 18507
• MGIID: 97489
• Length: 391
• Species: Mus musculus
• Alignment Length: 545
• Identity: 162/545 - (29%)
• Similarity: 214/545 - (39%)
• Gaps: 215/545 - (39%)

  Fly    98 HSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPR 162
            |.||||||||||.||||||..||:||||||.|.|||||||.|:||:||||||||||||||||:|.
Mouse    17 HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPG 81

  Fly   163 AIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQK 227
            .||||||:|||.:||.||::|||:.|::||||||||||.|.||.||.:||||||||::|....|.
Mouse    82 VIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQP 146

  Fly   228 EQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNS 292
            ..|...:.|.|..:..|::         .||:|::.|.|:..|.:.::...:|        ::::
Mouse   147 PNQPVPASSHSIVSTGSVT---------QVSSVSTDSAGSSYSISGILGITSP--------SADT 194

  Fly   293 GEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQ 357
            .:....|.|.|
Mouse   195 NKRKRDEGIQE------------------------------------------------------ 205

  Fly   358 QSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVA 422
                                  |..||             .||| |..|.
Mouse   206 ----------------------SPVPN-------------GHSL-PGRDF--------------- 219

  Fly   423 TEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLE 487
                 |:|::.|                                         ..||..|::.|:
Mouse   220 -----LRKQMRG-----------------------------------------DLFTQQQLEVLD 238

  Fly   488 KEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTS 552
            :.|||.||.|:|.                           ..|.::.::.|..|..||.......
Mouse   239 RVFERQHYSDIFT---------------------------TTEPIKPEQTTEYSAMASLAGGLDD 276

  Fly   553 ATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTL------------STNVNAPTLGAGI 605
            ..|:|| ||......||:    .|..|...:.|....||.            ..:.:||||...:
Mouse   277 MKANLT-SPTPADIGSSV----PGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMV 336

  Fly   606 DSSE-SPTPIPHIRPSCTSDNDNGR 629
            ..|| |.:|..|  |..:|.||:.|
Mouse   337 PGSEFSGSPYSH--PQYSSYNDSWR 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	93/122 (76%)
		Homeobox	475..527	CDD:278475	11/51 (22%)
Pax5	NP_032808.1	PAX	16..140	CDD:128645	93/122 (76%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	19..75		46/55 (84%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	94..142		32/47 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..218		11/133 (8%)
		Pax2_C	285..389	CDD:289189	21/81 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910