Protein Alignment ey and Pax4

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_035168.1
• Gene: Pax4 / 18506
• MGIID: 97488
• Length: 349
• Species: Mus musculus
• Alignment Length: 492
• Identity: 152/492 - (30%)
• Similarity: 185/492 - (37%)
• Gaps: 223/492 - (45%)

  Fly    99 SGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRA 163
            |.||||||:||.|||||..|||:||:||..|.|||||||.|:||||||||||||||.||.:.|:.
Mouse     7 SSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKC 71

  Fly   164 IGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKE 228
            |||||||:||..||::|:|.|.|.|::|||||:.:|..|.:||.|..|||||||||||
Mouse    72 IGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLR------- 129

  Fly   229 QQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSG 293
                                                                             
Mouse   130 ----------------------------------------------------------------- 129

  Fly   294 EGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQ 358
                                                                     |||:.|..
Mouse   130 ---------------------------------------------------------ALQEDQSL 137

  Fly   359 SWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVAT 423
            .|                            |...|...||..|..|:.           ||
Mouse   138 HW----------------------------TQLRSPAVLAPVLPSPHS-----------NC---- 159

  Fly   424 EDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEK 488
                               |.....:.|.|:                  ||||.|:..|.::|||
Mouse   160 -------------------GAPRGPHPGTSH------------------RNRTIFSPGQAEALEK 187

  Fly   489 EFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTP----------NSTG 543
            ||:|..|||..||.:||....|||..::||||||||||||:|||:.:.:.|          ||.|
Mouse   188 EFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPG 252

  Fly   544 ---ASATSSSTSATASLTDSPNSLSACSSLLSGSAGG 577
               |..:..|..:.|.....|.|.|.| .|..|:|.|
Mouse   253 IISAQQSPGSVPSAALPVLEPLSPSFC-QLCCGTAPG 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	82/121 (68%)
		Homeobox	475..527	CDD:278475	29/51 (57%)
Pax4	NP_035168.1	PAX	5..129	CDD:128645	82/121 (68%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64		43/55 (78%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131		28/176 (16%)
		Homeobox	174..226	CDD:278475	29/51 (57%)
		Transcription repression	278..349		5/12 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152885at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920