Protein Alignment ey and pax-3

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_496189.2
• Gene: pax-3 / 185022
• WormBaseID: WBGene00003939
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 124/519 - (23%)
• Similarity: 166/519 - (31%)
• Gaps: 234/519 - (45%)

  Fly    88 TYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGR 152
            |:.|:..   ...||||||||:.|||||...|..|:.:|..|.:||.|||.|:||:|.|||||.|
 Worm     7 TFNHILG---QGRVNQLGGVFINGRPLPIHVRHAIISMAKKGIKPCHISRQLKVSHGAVSKILNR 68

  Fly   153 YYETGSIRPRAIGGS-KPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSI 216
            |.|||||.|..|||| :.|:....|..:|.....|.|.:.|.|:||.|:.:::||..|.|:|.:|
 Worm    69 YAETGSISPGQIGGSPRARLTVQAVEKEILIACDENPQMSAAELRDWLIHKDICTKGNAPTVPAI 133

  Fly   217 NRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPL 281
            .|::.|         .|.|.........:|..:...:|.::...:..|
 Worm   134 KRLIGN---------KGVGVPKKMERKRLSYSIDSILGISIDECSKSS----------------- 172

  Fly   282 NSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVH 346
                    |:..|||
 Worm   173 --------SDDEEGS-------------------------------------------------- 179

  Fly   347 GNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLA 411
                                                                   ||.||..|
 Worm   180 -------------------------------------------------------SPSNDASS-- 187

  Fly   412 SIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRT 476
                                                                        :||||
 Worm   188 ------------------------------------------------------------RRNRT 192

  Fly   477 SFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNS 541
            |||.:|:|.||..|....||...|||.::.:.||.|.:|..|||||||:.|:...:..|... ..
 Worm   193 SFTAEQLDVLENAFRADTYPHANARESISKETGLSEEKIMTWFSNRRARCRKNMPMYQQYNV-QG 256

  Fly   542 TGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVST---INGL--------SSPSTLST 594
            .|:|..|..|     |..||....            ||.||   :|.|        |.||:.|:
 Worm   257 FGSSPPSYPT-----LLPSPMMFL------------PSYSTSPQLNPLFFQHILQSSPPSSQSS 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	60/123 (49%)
		Homeodomain	473..528	CDD:459649	28/54 (52%)
pax-3	NP_496189.2	PAX	13..141	CDD:238076	61/139 (44%)
		Homeodomain	188..244	CDD:459649	28/55 (51%)