DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and Otp

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_035151.1	Gene:	Otp / 18420	MGIID:	99835	Length:	325	Species:	Mus musculus

Alignment Length:	315	Identity:	90/315 - (28%)
Similarity:	127/315 - (40%)	Gaps:	79/315 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 PISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGS 442
            |...|||        |.|....:|.|..||.::.|.  ..:..|:.:|          ...:.|.
Mouse    42 PGDLAPN--------SDPVEGATLLPGEDITTVGST--PASLAVSAKD----------PDKQPGP 86

  Fly   443 GEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGK 507
            ..|.|    .|..|..:..|       |.:|:||.||..|::.||:.|.:|||||:|.||.||.:
Mouse    87 QGGPN----PSQAGQQQGQQ-------KQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALR 140

  Fly   508 IGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLS 572
            |||.|:|:||||.||||||::.:|..|..|.|         .:...|..|...|::.:|.::.:
Mouse   141 IGLTESRVQVWFQNRRAKWKKRKKTTNVFRAP---------GTLLPTPGLPQFPSAAAAAAAAM- 195

  Fly   573 GSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRV 637
                           ..|..|.:.|.....|......|..|:|   |:.      |||....:.:
Mouse   196 ---------------GDSLCSFHANDTRWAAAAMPGVSQLPLP---PAL------GRQQAMAQSL 236

  Fly   638 CSPCPLGVGGHQNTHHIQ-----SNGHA-QGH-------ALVPAISPRLNFNSGS 679
             |.|.|..|...|:..:.     |||.. |.|       .:|||..|..:..|||
Mouse   237 -SQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGS 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
Otp	NP_035151.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..112		23/100 (23%)
		Homeobox	107..156	CDD:395001	28/48 (58%)
		OAR	303..320	CDD:397759
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	306..319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910