DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and ceh-36

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_510365.1	Gene:	ceh-36 / 181529	WormBaseID:	WBGene00000457	Length:	257	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	73/258 - (28%)
Similarity:	100/258 - (38%)	Gaps:	62/258 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   468 KRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQ---VWFSNRRAKWRRE 529
            :|..:|.||||...|:|.|||.|..|.||||..||.||..|.||:.|:|   |||.|||||.|..
Worm    52 RRAGRRERTSFNRGQLDQLEKVFRETQYPDVHRREALAKAINLPDGRVQVITVWFKNRRAKDRNN 116

  Fly   530 EKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLST 594
            :|:....  |.||      ||.|                     |.|.|     :..|.|.|.|.
Worm   117 KKMDGVH--PGST------SSRS---------------------SNGSP-----HNESKPDTKSL 147

  Fly   595 NVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPC----PLGVGGHQNTHHIQ 655
            .::.|    |.....:.:...:...|........:|.:..::..|..    ||....:.:|..:.
Worm   148 GIHIP----GTPEFNAHSAAKYEANSAVLSQLQQQQQQQLQQPKSELEDSKPLADTKYDSTQSLL 208

  Fly   656 SNGHAQGHALVPAISP-RLNFNSGSFGAMY--SNMHHTALSMSDSYGAVTPIPSFNHSAVGPL 715
            ....|..:|.....:| ..|:||      |  ||.::.....:|    .||    |.:|..||
Worm   209 PQAQAAAYASYATTAPYPYNYNS------YFPSNFYYQQYGSND----YTP----NITAYSPL 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/54 (59%)
ceh-36	NP_510365.1	Homeobox	59..115	CDD:395001	32/55 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910