Protein Alignment ey and vab-3

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001024570.1
• Gene: vab-3 / 181251
• WormBaseID: WBGene00006870
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 242/652 - (37%)
• Similarity: 302/652 - (46%)
• Gaps: 225/652 - (34%)

  Fly    95 DECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSI 159
            |..|:||||||||||.||||||:|||:||:|||.|.|||||||:||||||||||||.||||:|:|
 Worm     3 DAGHTGVNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTI 67

  Fly   160 RPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLA 224
            ||||||||||||||::||.||..|||:.||||||||||:||.:|:|.|:.|||||||||||||||
 Worm    68 RPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNLA 132

  Fly   225 AQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGA 289
            |:|||.:                                           |||
 Worm   133 AKKEQVT-------------------------------------------MQT------------ 142

  Fly   290 SNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQ 354
                      .:|:::|:::
 Worm   143 ----------ELYDRIRIVD--------------------------------------------- 152

  Fly   355 HQQQSWPPRHYSGSWY---PTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQ 416
                ::|   |:.|||   |     ||::.|..:        .|.:...|..|.
 Worm   153 ----NFP---YNSSWYGQWP-----IPMNGAVGL--------NPFVPAPLIEPK----------- 186

  Fly   417 RNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTND 481
                  ||....|.|      |:....|.|            :|..||:.|||||||||||||..
 Worm   187 ------TEGEFEKDE------DQKPPTEPE------------DDAAARMRLKRKLQRNRTSFTQV 227

  Fly   482 QIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRR--------- 537
            ||:|||||||||||||||||||||.||.||||||||||||||||||||||:||:|.
 Worm   228 QIESLEKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWRREEKMRNKRSSGTMDSSLS 292

  Fly   538 --TPNSTGASATSSS-TSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAP 599
              ||..|..|.|.|: |:...|...:||...:     :.||..|   |.|.:...|.:...::.|
 Worm   293 NGTPTPTPGSVTGSNMTNPIGSPASTPNRFPS-----NNSANLP---TTNFVPQTSQMYAGLSQP 349

  Fly   600 TL---GAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQ 661
            .:   ..||.:..|..|.|.:..........||...|     .|.|          .:.:|||..
 Worm   350 AMDPYSFGIANGFSMAPYPQVTDFQPHHMFQGRSPYD-----FPYP----------RMPTNGHGF 399

  Fly   662 GHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGD 726
            ..::.||.:.     .|....:.|.|   :|.:|....::.  ||..||.:..|:         |
 Worm   400 QQSMSPATTA-----VGDIPTLSSGM---SLPVSAVLNSID--PSLTHSQMHELS---------D 445

  Fly   727 LT 728
            ||
 Worm   446 LT 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	97/122 (80%)
		Homeobox	475..527	CDD:278475	46/51 (90%)
vab-3	NP_001024570.1	PAX	5..129	CDD:128645	97/123 (79%)
		COG5576	183..293	CDD:227863	74/144 (51%)
		Homeobox	221..274	CDD:395001	47/52 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167869
Domainoid	1	1.000	213	1.000	Domainoid score	I1598
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I1246
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152885at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930