Protein Alignment ey and vab-3

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001024570.1
• Gene: vab-3 / 181251
• WormBaseID: WBGene00006870
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 242/652 - (37%)
• Similarity: 302/652 - (46%)
• Gaps: 225/652 - (34%)

  Fly    95 DECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSI 159
            |..|:||||||||||.||||||:|||:||:|||.|.|||||||:||||||||||||.||||:|:|
 Worm     3 DAGHTGVNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTI 67

  Fly   160 RPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLA 224
            ||||||||||||||::||.||..|||:.||||||||||:||.:|:|.|:.|||||||||||||||
 Worm    68 RPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNLA 132

  Fly   225 AQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGA 289
            |:|||.:                                           |||
 Worm   133 AKKEQVT-------------------------------------------MQT------------ 142

  Fly   290 SNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQ 354
                      .:|:::|:::
 Worm   143 ----------ELYDRIRIVD--------------------------------------------- 152

  Fly   355 HQQQSWPPRHYSGSWY---PTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQ 416
                ::|   |:.|||   |     ||::.|..:        .|.:...|..|.
 Worm   153 ----NFP---YNSSWYGQWP-----IPMNGAVGL--------NPFVPAPLIEPK----------- 186

  Fly   417 RNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTND 481
                  ||....|.|      |:....|.|            :|..||:.|||||||||||||..
 Worm   187 ------TEGEFEKDE------DQKPPTEPE------------DDAAARMRLKRKLQRNRTSFTQV 227

  Fly   482 QIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRR--------- 537
            ||:|||||||||||||||||||||.||.||||||||||||||||||||||:||:|.
 Worm   228 QIESLEKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWRREEKMRNKRSSGTMDSSLS 292

  Fly   538 --TPNSTGASATSSS-TSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAP 599
              ||..|..|.|.|: |:...|...:||...:     :.||..|   |.|.:...|.:...::.|
 Worm   293 NGTPTPTPGSVTGSNMTNPIGSPASTPNRFPS-----NNSANLP---TTNFVPQTSQMYAGLSQP 349

  Fly   600 TL---GAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQ 661
            .:   ..||.:..|..|.|.:..........||...|     .|.|          .:.:|||..
 Worm   350 AMDPYSFGIANGFSMAPYPQVTDFQPHHMFQGRSPYD-----FPYP----------RMPTNGHGF 399

  Fly   662 GHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGD 726
            ..::.||.:.     .|....:.|.|   :|.:|....::.  ||..||.:..|:         |
 Worm   400 QQSMSPATTA-----VGDIPTLSSGM---SLPVSAVLNSID--PSLTHSQMHELS---------D 445

  Fly   727 LT 728
            ||
 Worm   446 LT 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	97/122 (80%)
		Homeodomain	473..528	CDD:459649	49/54 (91%)
vab-3	NP_001024570.1	PAX	5..129	CDD:128645	97/123 (79%)
		Homeodomain	219..274	CDD:459649	49/54 (91%)