DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and ceh-51

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_507685.1	Gene:	ceh-51 / 180233	WormBaseID:	WBGene00013583	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	290	Identity:	63/290 - (21%)
Similarity:	105/290 - (36%)	Gaps:	91/290 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 SAKVSVSIGGNVSNVASGSRGTLSSSTD--LMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLL 308
            |:..:::.||:...::|.:..:.|:.|:  :|:.:| :.||..|..|:|
Worm     3 SSNYNINNGGDYYPLSSSNLNSTSAITNATVMEYST-MPSSSPGSMSSS---------------- 50

  Fly   309 NTQHAAGPGPLEPA---RAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWY 370
                     |..||   ..:|.....||.|..:.   ||.|..:..|.|...|::..:.:  :|:
Worm    51 ---------PAYPAAYQAPSPCYVADPNQLYYQQ---QLAHNGNDMLVQAHAQAYQAQCF--AWF 101

  Fly   371 PTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGH 435
            ....|::..||.|:          |.:||               |....|.....:|       |
Worm   102 QQQYSQLSPSSFPH----------PMVAH---------------HAGFIPPPPSFLH-------H 134

  Fly   436 QSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFA 500
            |..:......|...|.                       ||.|::.|:.:|...||:.....|..
Worm   135 QHQQHPRAPSEKRRGA-----------------------RTPFSDSQLYALRTRFEQCDTIKVDE 176

  Fly   501 RERLAGKIGLPEARIQVWFSNRRAKWRREE 530
            |.:|...|||...:|::||.|||.|.|:|:
Worm   177 RRKLGAVIGLSPEQIKIWFQNRRFKLRKEK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	20/51 (39%)
ceh-51	NP_507685.1	Homeobox	151..204	CDD:365835	20/52 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940