DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and unc-30

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001021277.1	Gene:	unc-30 / 178265	WormBaseID:	WBGene00006766	Length:	323	Species:	Caenorhabditis elegans

Alignment Length:	323	Identity:	92/323 - (28%)
Similarity:	125/323 - (38%)	Gaps:	112/323 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 NIASVTAY---------ASGPSLA------HSLSPPNDI-ESLASIGH-----QRNCPVATEDI- 426
            |.|::||.         .|.|.:.      |||.|.:.| .|||.:.|     ..:.|:...||
Worm     4 NTATLTAIHQQQQSHNRFSNPLVCVGQLDHHSLLPEHSISSSLAPLTHNPYAFNYSIPLPPTDIT 68

  Fly   427 -----------HLKKELDGHQ------SDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRN 474
                       .:|:|.|.:.      :|.||:|   ::|||..               :|.:|.
Worm    69 TKLPKLELLSLDVKQEQDDNHLDTSSPTDSTGNG---STNGGKI---------------QKPRRQ 115

  Fly   475 RTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEK---LRNQR 536
            ||.||:.|:..||..|.|..|||:..||.:|..|.|.|.|::|||.|||||||:.|:   :.|.:
Worm   116 RTHFTSHQLTELENWFSRNRYPDMACREEIAVWISLTEPRVRVWFKNRRAKWRKRERNYVIDNGQ 180

  Fly   537 RTPNSTGASATSSSTSATASLTDS-PNS-LSACSSLLSGSA---------GG-----PSVSTING 585
            .|     ...|:.|.....||.:: |.: |.:.||.|..||         ||     |..|..|.
Worm   181 GT-----TKVTAQSLDPLGSLQNTFPQTLLQSSSSQLDDSAVTSSSFYGYGGAWQQNPYYSRNNQ 240

  Fly   586 LS------------------SPST----LSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDND 626
            .:                  ||:|    .||..|...|         ||.......|.||.||
Worm   241 TTFNWQIKPQDQFQFQTIPMSPTTATSRFSTAANLAPL---------PTAQAAFSTSATSSND 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	27/51 (53%)
unc-30	NP_001021277.1	Homeobox	116..168	CDD:278475	27/51 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910