DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and egl-38

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_501836.1	Gene:	egl-38 / 177876	WormBaseID:	WBGene00001204	Length:	289	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	118/308 - (38%)
Similarity:	160/308 - (51%)	Gaps:	76/308 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 LTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYET 156
            |..|..|:||||||||||.||||.|:.|.:|||::..|.|||||||.|:||:|||||||||||.|
Worm    24 LLSDGSHTGVNQLGGVFVNGRPLADTVRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYST 88

  Fly   157 GSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLR 221
            ||:||..||||||:|||..||..|:.|||..|::||||||.:|:::.:|..:|:||||||||::|
Worm    89 GSVRPGVIGGSKPKVATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVR 153

  Fly   222 NLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSES 286
            |.:...:                ::|..||:        :|.:|.  ||:|...|.:.|....:.
Worm   154 NKSFMAQ----------------LAAPTSVT--------SSAARP--SSATSHHQRSPPRGVQQH 192

  Fly   287 GGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPL--EPARAAP--------LVGQSP--------- 332
                     .:|....::|:.|....||....|  .||.|.|        |:|..|
Worm   193 ---------MQQSTSVQQLQQLQLTSAATVNSLMTPPAFAMPGTAYSINGLLGTLPQPSLLDDKF 248

  Fly   333 NHLGTRSSHPQLVH-----GNHQALQQHQQQSWP--------PRHYSG 367
            .:|.|:|:...||:     |.|         .|.        |::|.|
Worm   249 TNLSTQSADMSLVYSTGLVGEH---------DWTMRTPMVILPQNYCG 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	80/122 (66%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475
egl-38	NP_501836.1	PAX	29..153	CDD:128645	80/123 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910