DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Msx3

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_034966.1	Gene:	Msx3 / 17703	MGIID:	106587	Length:	204	Species:	Mus musculus

Alignment Length:	140	Identity:	39/140 - (27%)
Similarity:	60/140 - (42%)	Gaps:	24/140 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 GHQRN--CPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQAR------------ 464
            ||..:  .|.:.|.:...:.:.|.:|.|.    |.....|||..|......|.
Mouse    19 GHTEHGPLPFSVESLLEAERVPGSESGEL----GVERPLGASKPGAWPPPVAHSCPPRAPSPPPC 79

  Fly   465 LILKRKLQRN-RTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR 528
            .:.|.|..|. ||.||..|:.:||::|.:..|..:..|...:..:.|.|.::::||.|||||.:|
Mouse    80 TLRKHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 144

  Fly   529 -----EEKLR 533
                 .|||:
Mouse   145 LQEAELEKLK 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
Msx3	NP_034966.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..89		11/53 (21%)
Msx3	NP_034966.1	Homeobox	90..143	CDD:278475	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910