DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and nob-1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001369824.1	Gene:	nob-1 / 176641	WormBaseID:	WBGene00003779	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	53/227 - (23%)
Similarity:	80/227 - (35%)	Gaps:	69/227 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 WYPTSLSEIP-------------ISSAPNIA----------SVTAYASGPSLAHSLSPPNDI--- 407
            ::|::.:.||             ..|:|.:|          :...|..|||   .:...|:.
Worm    30 FWPSAAAAIPSIQGESRSERESETGSSPQLAPSSTGMVMPGTAGMYGFGPS---RMPTANEFGMM 91

  Fly   408 ----------ESLASIG-HQRNCPVATEDIHLKKELDGHQSDET-----GSGEGENSNG------ 450
                      ..|||.| :....|......:....|||:.||.|     ||......|.
Worm    92 MNPVYTDFYQNPLASTGWYSYGQPYQFTANYSIPSLDGNLSDITIPTTAGSSAATTPNAAMHLPW 156

  Fly   451 GASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARI 515
            ..|:.|               ::.|..:..|||..||.|:....|.....|..|:.::.|.|.::
Worm   157 AISHDG---------------KKKRQPYKKDQISRLEYEYSVNQYLTNKRRSELSAQLMLDEKQV 206

  Fly   516 QVWFSNRRAKWRREEKLRNQRRTPNSTGASAT 547
            :|||.|||.|   ::|||.:...|...||..|
Worm   207 KVWFQNRRMK---DKKLRQRHSGPFPHGAPVT 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
nob-1	NP_001369824.1	Homeobox	165..219	CDD:395001	19/56 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910