DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and lin-39

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001021164.1	Gene:	lin-39 / 176068	WormBaseID:	WBGene00003024	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	294	Identity:	74/294 - (25%)
Similarity:	112/294 - (38%)	Gaps:	88/294 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 TLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQS 331
            |..||||..:...|.:||.|..:|:|..              :|......|....:..:..:|..
Worm     5 TSPSSTDAPRATAPESSSSSSSSSSSSS--------------STSSVGASGIPSSSELSSTIGYD 55

  Fly   332 PNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWY-PTSLSEIPISSAPNIASVTAYASGP 395
            |.   |.|:          ||..|          .||:| |||.|:|          .:.:||..
Worm    56 PM---TASA----------ALSAH----------FGSYYDPTSSSQI----------ASYFASSQ 87

  Fly   396 SLAHSLSPPNDIESLASIGHQRNC--PVATEDIHLKKELDGHQSDETG------SGEGEN---SN 449
            .|.....|        .:|.|..|  |..|...|..|.|:|...|:..      ||:.::   ::
Worm    88 GLGGPQYP--------ILGDQSLCYNPSVTSTHHDWKHLEGDDDDDKDDDKKGISGDDDDMDKNS 144

  Fly   450 GGA---------SNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLA 505
            |||         |..|.:..:          :|.||::|.:|:..|||||....|.....|..:|
Worm   145 GGAVYPWMTRVHSTTGGSRGE----------KRQRTAYTRNQVLELEKEFHTHKYLTRKRRIEVA 199

  Fly   506 GKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTP 539
            ..:.|.|.::::||.|||.|.::|.|  ::..||
Worm   200 HSLMLTERQVKIWFQNRRMKHKKENK--DKPMTP 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	20/51 (39%)
lin-39	NP_001021164.1	Homeobox	169..221	CDD:278475	20/51 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910