DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Lhx8

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_034843.2	Gene:	Lhx8 / 16875	MGIID:	1096343	Length:	367	Species:	Mus musculus

Alignment Length:	124	Identity:	39/124 - (31%)
Similarity:	58/124 - (46%)	Gaps:	27/124 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   444 EGENSNG----GASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERL 504
            |.||.||    ||.   .||.|...   .:..:|.|||||.||:..::.:|.:.:.||....::|
Mouse   221 EVENGNGISVEGAL---LTEQDVNH---PKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKL 279

  Fly   505 AGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNS 563
            |.:.||....|||||.|.||:.::.                 .|.:.|::|.:|..|:|
Mouse   280 AERTGLSRRVIQVWFQNCRARHKKH-----------------VSPNHSSSAPVTAVPSS 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
Lhx8	NP_034843.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..79
		LIM1_Lhx7_Lhx8	95..150	CDD:188767
		LIM2_Lhx7_Lhx8	157..211	CDD:188769
		Homeobox	250..302	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030