DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Hoxa5

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_034583.1	Gene:	Hoxa5 / 15402	MGIID:	96177	Length:	270	Species:	Mus musculus

Alignment Length:	296	Identity:	71/296 - (23%)
Similarity:	107/296 - (36%)	Gaps:	89/296 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 GTLSSSTDLMQTATPLNSSESG----------GASNSGE-GSEQEAIYEKLRLLNTQHAAG--PG 317
            |..||.::..:.:..::|...|          |.|.||. ||.:.|         ..:|||  ..
Mouse    25 GDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERA---------RSYAAGASAA 80

  Fly   318 PLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISS- 381
            |.||..:.|          ..|:|                 |.||            ..:|.|:
Mouse    81 PAEPRYSQP----------ATSTH-----------------SPPP------------DPLPCSAV 106

  Fly   382 APNIASVTAYASGPSLAHSL-----SPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETG 441
            ||:..|.:.:....||.:|.     :....|.|...:|   ....|.||.....|..|.||:.:.
Mouse   107 APSPGSDSHHGGKNSLGNSSGASANAGSTHISSREGVG---TASAAEEDAPASSEQAGAQSEPSP 168

  Fly   442 SGEGE--------NSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDV 498
            :...:        ..:....|||..|.           :|.||::|..|...|||||....|...
Mouse   169 APPAQPQIYPWMRKLHISHDNIGGPEG-----------KRARTAYTRYQTLELEKEFHFNRYLTR 222

  Fly   499 FARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRN 534
            ..|..:|..:.|.|.:|::||.|||.||:::.||::
Mouse   223 RRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKS 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
Hoxa5	NP_034583.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	75..175		29/141 (21%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeobox	199..252	CDD:333795	22/52 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910