DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Hoxa11

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_034580.1	Gene:	Hoxa11 / 15396	MGIID:	96172	Length:	313	Species:	Mus musculus

Alignment Length:	252	Identity:	61/252 - (24%)
Similarity:	105/252 - (41%)	Gaps:	44/252 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 SEQEAIYEKLRLLNTQHAAG-PGPLEPARAA-----PLVGQSPNHLGTRSSHPQLVHGNHQALQQ 354
            |.:|.::..  .|....||| ||.:....:|     |....|.|...|...:..|    .||..|
Mouse    85 SAEELVHRD--CLQAPSAAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVL----PQAFDQ 143

  Fly   355 HQQQSW-PPRHYSGSWYP--TSLSEIP-ISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGH 415
            ..:.:: .|.:.:.|.||  .:..:.| .::|.:.|:|.|.|:|.....|          :..|.
Mouse   144 FFETAYGTPENLASSDYPGDKNAEKGPQAAAATSAAAVAAAATGAPATSS----------SDGGG 198

  Fly   416 QRNC-PVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFT 479
            ...| ..|.|:...::..:...|.|:.||..|:..||:..              ::.::.|..:|
Mouse   199 GGGCQEAAAEEKERRRRPESSSSPESSSGHTEDKAGGSGG--------------QRTRKKRCPYT 249

  Fly   480 NDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQR 536
            ..||..||:||..:.|.:...|.:|:..:.|.:.::::||.|||.|   |:|:...|
Mouse   250 KYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMK---EKKINRDR 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	18/51 (35%)
Hoxa11	NP_034580.1	DUF3528	26..168	CDD:288866	21/88 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..246		12/81 (15%)
		Homeobox	244..297	CDD:278475	18/55 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910