DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Hmx3

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_032283.3	Gene:	Hmx3 / 15373	MGIID:	107160	Length:	356	Species:	Mus musculus

Alignment Length:	328	Identity:	79/328 - (24%)
Similarity:	121/328 - (36%)	Gaps:	84/328 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 QEAIYEKLRLLN-TQHAAGPGPLEPARA--APLVGQSPNHLGTRSSHPQLVHGNHQ-ALQQHQQQ 358
            :|:.:....||| ..|...|.|..|.|.  ||....:.......::....:.|... ||.|....
Mouse    27 KESPFSIRNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDL 91

  Fly   359 SWP-----------PRHY----SGSWYPTSLS----EIPISSAPNIASVTAYASGPSLAHSLSPP 404
            ::|           |.||    ...|||.:|:    .:|   .|.       ||..:|....||.
Mouse    92 AFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLP---RPE-------ASEKALLRDSSPA 146

  Fly   405 NDIESLASIGHQRNCP---VATEDIHLKKELDGHQSD---------ETGSGEGENSNGGA-SNIG 456
            :        |..|:.|   :..:..|  ||||....|         |.|..|||...|.| :.:|
Mouse   147 S--------GTDRDSPEPLLKADPDH--KELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVG 201

  Fly   457 NT-------------EDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKI 508
            .|             |..:.:...::|  :.||.|:..|:..||..|:...|.....|..||..:
Mouse   202 ATTATPGSEDWKAGAESPEKKPACRKK--KTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASL 264

  Fly   509 GLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASA-----------TSSSTSATASLTDSPN 562
            .|.|.::::||.|||.||:|:  |..:....|.:.|:|           .:|:....|:...:|.
Mouse   265 HLTETQVKIWFQNRRNKWKRQ--LAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAGAPV 327

  Fly   563 SLS 565
            .:|
Mouse   328 PVS 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
Hmx3	NP_032283.3	Homeobox	230..284	CDD:365835	20/53 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910