DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Gsx1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_032204.1	Gene:	Gsx1 / 14842	MGIID:	95842	Length:	261	Species:	Mus musculus

Alignment Length:	229	Identity:	57/229 - (24%)
Similarity:	83/229 - (36%)	Gaps:	59/229 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 PSLAHSLSPPNDIESLA-SIGHQRN------CP--VATEDIH----------LKKE--------- 431
            |...:::.||:.:..|: ...|.|.      ||  |....:|          ||..
Mouse    27 PLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYC 91

  Fly   432 ---LDGHQSDETGSGEGENSNGGASNIGNTE--------------DDQARLILKRKLQRNRTSFT 479
               |....|...|...|..:...|:.:..|.              |..:..:...|  |.||:||
Mouse    92 HAPLGRQHSVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSK--RMRTAFT 154

  Fly   480 NDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGA 544
            :.|:..||:||....|.....|..:|..:.|.|.::::||.|||.|.::|.|..|.|   ...||
Mouse   155 STQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHR---GGAGA 216

  Fly   545 SA---------TSSSTSATASLTDSPNSLSACSS 569
            .|         .||.:||..|..|....:|..||
Mouse   217 GAGGGAPQGCKCSSLSSAKCSEDDDELPMSPSSS 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	20/51 (39%)
Gsx1	NP_032204.1	SNAG domain. /evidence=ECO:0000250	1..20
		Homeobox	150..203	CDD:395001	20/52 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..261		16/53 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910