DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Gsc

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_034481.1	Gene:	Gsc / 14836	MGIID:	95841	Length:	256	Species:	Mus musculus

Alignment Length:	257	Identity:	69/257 - (26%)
Similarity:	106/257 - (41%)	Gaps:	62/257 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 PLEPARAAPLV-----GQSPNHL--GTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLS 375
            |:.|:.|||:|     |.|....  ||.|.:                         |::||.
Mouse    24 PVAPSAAAPVVFPALHGDSLYGAGGGTSSDY-------------------------GAFYPR--- 60

  Fly   376 EIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDET 440
              |:  ||..|.:.|......|.::......:       |.:..||..........|...|....
Mouse    61 --PV--APGGAGLPAAVGSSRLGYNSYFYGQL-------HVQAAPVGPACCGAVPPLGAQQCSCV 114

  Fly   441 GSGEGENSNGGA------------SNIGNTEDDQARLILK---RKLQRNRTSFTNDQIDSLEKEF 490
            .:..|....|..            .|:|.....:.:|:.:   |:.:|:||.||::|:::||..|
Mouse   115 PTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQLHCRRKRRHRTIFTDEQLEALENLF 179

  Fly   491 ERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTS 552
            :.|.||||..||:||.|:.|.|.:::|||.|||||||| :|..:...:.|:...:.|||..|
Mouse   180 QETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRR-QKRSSSEESENAEKWNKTSSKAS 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	28/51 (55%)
Gsc	NP_034481.1	Homeobox	163..216	CDD:278475	28/52 (54%)
Gsc	NP_034481.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..256		11/29 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940