DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and dmbx1a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_694509.1	Gene:	dmbx1a / 142987	ZFINID:	ZDB-GENE-020117-1	Length:	388	Species:	Danio rerio

Alignment Length:	339	Identity:	99/339 - (29%)
Similarity:	145/339 - (42%)	Gaps:	95/339 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 RKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR----- 528
            ||.:|:||:||..|:::|||.|::||||||..|||||....|||||:||||.|||||:|:
Zfish    69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSL 133

  Fly   529 -EEKLRNQRRTPNSTGASATSSSTSA--TASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPS 590
             :|:|:.|:.. ::.||.|.|....|  |.:|.:.|.|.::.||.:...|...::.        |
Zfish   134 QKEQLQKQKDV-STDGALAASDKDEAPSTLNLENQPPSSTSSSSSMEAEAAPHALG--------S 189

  Fly   591 TLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSED---------------------C 634
            .||..:|..:  |....||          |.|.||...::.|.                     |
Zfish   190 ELSVELNVTS--AEQSGSE----------SATEDNATDKEEEIKQHREDLKVEKEPAPGNLSPLC 242

  Fly   635 RRVCSP---CPLGVGGHQNTHHIQSNGHAQGHALVPAISP----RLNFNSGSFGAMYSNMHHTAL 692
            :|: ||   .|||.....::....:.|.:|.|:.  :.||    ||........|..:|:.|
Zfish   243 KRL-SPKPDSPLGSPAISSSSSGVTGGISQSHSY--SSSPLSLFRLQEQFRQHMAATNNLVH--- 301

  Fly   693 SMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQG----DLTPSSLYPCHMTLRPPPMAPAHH---- 749
                       .|||:      :|.||.||..|    ...|....||....:    :.:||
Zfish   302 -----------YPSFD------MATPSSIPYLGMNVNMPAPLGSLPCQSYYQ----SLSHHAQQV 345

  Fly   750 ---HIVPGDGGRPA 760
               .::...||.|:
Zfish   346 WNSPLLQASGGLPS 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	34/51 (67%)
dmbx1a	NP_694509.1	Homeobox	74..127	CDD:278475	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..272		35/164 (21%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	365..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940