DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP005311

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_315326.4	Gene:	AgaP_AGAP005311 / 1276025	VectorBaseID:	AGAP005311	Length:	349	Species:	Anopheles gambiae

Alignment Length:	471	Identity:	115/471 - (24%)
Similarity:	181/471 - (38%)	Gaps:	159/471 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   375 SEIPISSAPNIASVTAYASGPSLAHSL-------------SPPNDIESLASIGHQRNCPVATEDI 426
            :|..|.:.|..:::|.    |...:|:             |.||:..:..:|.:..|.....|:
Mosquito    11 AERVIRAPPQSSAITK----PRAVYSIDQILGNHHHTRRTSGPNNNNNSLTINNNNNSSPDHEN- 70

  Fly   427 HLKKELDGHQSDETGSGEGENSN-----GGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSL 486
            .||:|....:..:.|. :.:|.:     |....:.|..:|..|   .||::|:||:||..|:..|
Mosquito    71 SLKREGSPVEVHDNGV-DVDNDDELPIMGDIDPMDNDPNDMGR---PRKIRRSRTTFTTYQLHQL 131

  Fly   487 EKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSST 551
            |:.||:|.|||||.||.||.::.|.|||:||||.|||||||:.||              |....|
Mosquito   132 ERAFEKTQYPDVFTREELAMRLDLSEARVQVWFQNRRAKWRKREK--------------AMGRDT 182

  Fly   552 SATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPT---- 612
            ||                .|....|.|...    |:.|  |:.|:..|.|         ||
Mosquito   183 SA----------------FLHHEQGMPEFP----LALP--LTHNIPHPAL---------PTEFWP 216

  Fly   613 PIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNS 677
            |...:.||                      |..|.|...|              |.:.|  |:..
Mosquito   217 PNFGLHPS----------------------LLPGAHGLLH--------------PNVMP--NYKI 243

  Fly   678 GSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPP 742
            .:|.|:.|..    :.:::.:|...     .:.::.....|...|:|   :|:|:.|..:
Mosquito   244 PNFHAILSQY----MGLNNLFGGYP-----QNLSINTRISPQNSPKQ---SPTSVQPTMV----- 291

  Fly   743 PMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAA 807
                          |.|.|:...|..|.|.|||       :||:       ..|||::.||.|::
Mosquito   292 --------------GGPVGINNTSNSSTNSGAS-------ILSS-------SNSSSSSSSSSSSS 328

  Fly   808 SSASANVTPHHTIAQE 823
            |.:::|::.....::|
Mosquito   329 SGSNSNISVGSNTSKE 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
AgaP_AGAP005311	XP_315326.4	Homeobox	119..172	CDD:278475	32/52 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910