Protein Alignment ey and Poxn

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_314947.5
• Gene: Poxn / 1275678
• VectorBaseID: AGAMI1_009473
• Length: 636
• Species: Anopheles gambiae
• Alignment Length: 650
• Identity: 180/650 - (27%)
• Similarity: 241/650 - (37%)
• Gaps: 235/650 - (36%)

  Fly    99 SGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRA 163
            :||||||||||.||||||..|::|||||..|.|||||||.|.||:|||||||.|:||||||||.:
Mosquito    82 AGVNQLGGVFVNGRPLPDIVRRRIVELALMGVRPCDISRQLLVSHGCVSKILTRFYETGSIRPGS 146

  Fly   164 IGGSKPR-VATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQK 227
            |||||.: |||..||.||.::|:|.|.:|||||||:||.:.:|..:.||||||:||:|||
Mosquito   147 IGGSKTKQVATPTVVKKILRFKQENPGMFAWEIRDQLLSQRICDPNTIPSVSSVNRILRN----- 206

  Fly   228 EQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNS 292
                .|..:...::...:..:.|.|....:.:.|..|....|.:  |.|....||......|:.|
Mosquito   207 ----GGMWTDDMTSNEQMLRESSHSSSAYMQSKAMSSHPLYSQT--LEQHQALLNQYRYSMAAVS 265

  Fly   293 GEGSEQEAIYEKLRLLNTQH--------AAGPGPLEPARAAPLVGQ--SPNHLGTRSSHPQLVHG 347
            .:.:.:..        |..|        ...|||:....||..:.|  |....||....|::.|.
Mosquito   266 PDHASKHP--------NLPHHHSPYGSPPGAPGPMVQRTAAVNIIQHESLPPTGTTKQPPEMHHQ 322

  Fly   348 N----------------HQALQQHQQQ----------SWP----PR------HYSGSWYPTSLSE 376
            :                ||....|.||          |.|    |:      ..|.|...|....
Mosquito   323 HTVSPLQTQPLTAGHNPHQHHHHHHQQQQHGKPSPSVSMPDLSSPKGGDSKSEPSSSTRSTPTGS 387

  Fly   377 IPISSAP--------------------------------------NIASVTAYASGPSLAHSLSP 403
            .|:||||                                      :.|:..|.|:..:.|.:..|
Mosquito   388 TPVSSAPPNPAQMPYLPKHWIWNTSLFYAANRGQHAPGADPSTVSSAAAAAAAAAAAAAAAAAFP 452

  Fly   404 ----------------PNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGA 452
                            |..|||                        ..:||.|.|    |::...
Mosquito   453 HGYFTYGNPFGGGAPFPGQIES------------------------SLRSDTTAS----NASSSP 489

  Fly   453 SNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQV 517
            ..|.:...|.                ::|..|.|.....:...|  ::.|.|..|   ||:
Mosquito   490 VQITDVNSDD----------------SSDNHDELRTSISKKRNP--YSIEELLKK---PES---- 529

  Fly   518 WFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLS----ACSSLLSGSAGGP 578
                      :::|:.::        .:.|..|.|:..:.||||....    .||         |
Mosquito   530 ----------KKQKIDDR--------VTITCISDSSRKTPTDSPLDDKYHHYQCS---------P 567

  Fly   579 SVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDND---------NGRQSEDC 634
            ||       |||               .|..|||.||.....|.|.:|         .|..||.|
Mosquito   568 SV-------SPS---------------KSCPSPTGIPVTAVRCKSSSDYRSSSSPQSAGEDSEGC 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	82/122 (67%)
		Homeodomain	473..528	CDD:459649	9/54 (17%)
Poxn	XP_314947.5	None