DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP004659

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_311616.1	Gene:	AgaP_AGAP004659 / 1272726	VectorBaseID:	AGAP004659	Length:	372	Species:	Anopheles gambiae

Alignment Length:	366	Identity:	86/366 - (23%)
Similarity:	134/366 - (36%)	Gaps:	114/366 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 VSNVAS----GSRGTLSSSTDLMQTATPLNSSESGGASNSG---EGSEQEAIYEKLRLLNTQHAA 314
            |:::||    .|:.|.||.          |::.|.|:.|.|   ..:....||.     .|.|.|
Mosquito    14 VNSIASCYPNNSQNTNSSP----------NTAGSQGSQNDGYFPPSTYAPNIYP-----GTPHQA 63

  Fly   315 GPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQAL----------------QQHQQQSWPPR 363
               ...|....||.|.....:.:.|:  ..|.|.||:.                ||.|.||....
Mosquito    64 ---HYSPQSYNPLAGAGATSVNSAST--GAVGGGHQSTDMVDYTQLQPQKFLLSQQQQPQSALTS 123

  Fly   364 H---YSGSWYPTSLSEI------PISSAPNIASVTAYASG--------PSLAHSLSPPNDIESLA 411
            .   |:.....|..:.|      ..:|..::::.:..:||        |.::..|||.:.:||::
Mosquito   124 QSCKYASEGPSTGTNVINNNNNNSTTSPQDLSTASGGSSGANDGNNGRPEISPKLSPGSVVESVS 188

  Fly   412 ------------------------SIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGA 452
                                    |..:|.|.|:|:      .|.:...||:....||.:|.||.
Mosquito   189 RSLKSGNPSTAVSSSSTNNNTSNISNRNQVNLPLAS------PEEESEASDDDSGTEGGSSQGGG 247

  Fly   453 S-------------------NIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDV 498
            .                   :||     |:.:....:.:|.|||:|..|...|||||....|...
Mosquito   248 GSSSKKGGPPPHIYPWMKRVHIG-----QSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTR 307

  Fly   499 FARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTP 539
            ..|..:|..:.|.|.:|::||.|||.||::|.|:.:....|
Mosquito   308 RRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVP 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
AgaP_AGAP004659	XP_311616.1	Homeobox	284..336	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910