DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP000488

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_310605.5	Gene:	AgaP_AGAP000488 / 1271752	VectorBaseID:	AGAP000488	Length:	598	Species:	Anopheles gambiae

Alignment Length:	406	Identity:	95/406 - (23%)
Similarity:	151/406 - (37%)	Gaps:	98/406 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 QKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGAS 290
            |::|||...|.::|:.|.: |..:| ||......||....|.::....|..:|....::.:...|
Mosquito   245 QQQQQSPTVGKTATNPGYT-SFSIS-SILSRTEPVAKKGLGVITPVPSLPLSAEAAAAAAAASVS 307

  Fly   291 N-------SGEGSEQE-AIYEKLRLLN------TQHAA--GPGPLEPARAAPLVGQSPNHLGTRS 339
            |       :|..|.|: |:..:|..::      .::||  .||...|    |...:.|.|..|..
Mosquito   308 NGTVSLGSNGTPSTQDAAMLSRLGFMSQWSAIANRYAALCPPGWPWP----PTSHRMPFHSPTND 368

  Fly   340 SHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYAS----------- 393
            :       :..|::.......||        |:..|:.|   :|:.|.:...||
Mosquito   369 N-------STNAMENQSPSLTPP--------PSQQSKSP---SPHPAFLGGRASGCGPGGPGGMG 415

  Fly   394 ------GPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGA 452
                  ||.....|.|.:|.|| ...|.:    :..||         .:||........||||.|
Mosquito   416 GPGTGVGPGGPGGLGPGDDCES-DDDGQE----IIEED---------DESDRPSDSASPNSNGSA 466

  Fly   453 SNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQV 517
            .        ||    ||| ::.||.|:..|:..||..|:...|.....|..||..:.|.|.::::
Mosquito   467 M--------QA----KRK-KKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKI 518

  Fly   518 WFSNRRAKWRREEKLRNQRRTPNSTGASATS------------SSTSATASLTDSPNSLSACSSL 570
            ||.|||.||:|:  |..:....|....:..:            .:|.........|:|.....:.
Mosquito   519 WFQNRRNKWKRQ--LAAELEAANMANMAHAAQRLVRVPVLYHEGATGGFVPPPPHPHSQQLYYTT 581

  Fly   571 LSGSAGGPSVSTINGL 586
            .:|.||.|....::.|
Mosquito   582 SAGRAGSPPRPPLSSL 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
AgaP_AGAP000488	XP_310605.5	Homeobox	475..528	CDD:278475	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910