DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP009500

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_310195.4	Gene:	AgaP_AGAP009500 / 1271410	VectorBaseID:	AGAP009500	Length:	400	Species:	Anopheles gambiae

Alignment Length:	538	Identity:	105/538 - (19%)
Similarity:	158/538 - (29%)	Gaps:	217/538 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GLGGIAGKPSPTM----EAVEASTASHPHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLP 115
            ||||:||.....:    :|::|..||.......|.
Mosquito    33 GLGGLAGLSGQDIGMLQQALQAQQASLQQQLQQYM------------------------------ 67

  Fly   116 DSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKI 180
                                  :|||..|..|                ..|:....|||: ....
Mosquito    68 ----------------------LLQVQGGAAS----------------ANGNAAAAATAQ-AQAA 93

  Fly   181 SQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLR---------NLAAQKEQQSTGSGS 236
            :|:               |:|..||:       ||.::...         :.|.||:||...:.|
Mosquito    94 AQF---------------LMQNQVCS-------SSAHQQWECRRHRQRGTDRALQKQQQLKPTSS 136

  Fly   237 SSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSES----------GG--- 288
            :.|....:.|:.:         :..|||.|....||   ||...|.:|::          ||
Mosquito   137 TPTPGATATSSPL---------HSPSGSPGLHHHST---QTGAMLGASQTTPPNVSQLNVGGILT 189

  Fly   289 ASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPA-----------RAAPLVGQSPNHLGTRSSHP 342
            .|..|.|:....:        .:|:|.|..|||:           :.|....|....||......
Mosquito   190 PSTPGSGAHTPQL--------QKHSAAPRALEPSPEETTDLEELEQFAKTFKQRRIKLGFTQGDV 246

  Fly   343 QLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDI 407
            .|..|               :.|...:..|::|.                              .
Mosquito   247 GLAMG---------------KLYGNDFSQTTISR------------------------------F 266

  Fly   408 ESLASIGHQRNC---PVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKR 469
            |:| ::..:..|   |:      |:|.|:...|..:..|....|....||...|.:...|   :|
Mosquito   267 EAL-NLSFKNMCKLKPL------LQKWLEDADSSISNPGGRIFSPAALSNTMATPETMGR---RR 321

  Fly   470 KLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRN 534
            |   .|||.......:|||.|.....|.......||..:.:.:..::|||.|||.|        .
Mosquito   322 K---KRTSIETSVRVALEKAFLVNCKPTSEEISTLADNLCMEKEVVRVWFCNRRQK--------E 375

  Fly   535 QRRTPNSTGASATSSSTS 552
            :|..|.:...|.|.||.|
Mosquito   376 KRINPPNGMDSPTHSSAS 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	16/122 (13%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	17/51 (33%)
AgaP_AGAP009500	XP_310195.4	POU	227..291	CDD:197673	16/115 (14%)
AgaP_AGAP009500	XP_310195.4	Homeobox	323..376	CDD:278475	17/60 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910