DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and AgaP_AGAP011134

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_309513.3	Gene:	AgaP_AGAP011134 / 1270792	VectorBaseID:	AGAP011134	Length:	501	Species:	Anopheles gambiae

Alignment Length:	391	Identity:	88/391 - (22%)
Similarity:	117/391 - (29%)	Gaps:	126/391 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   404 PNDIESLASIG------HQRNCPVATEDIHLKK----ELDGHQSDETGSGEGENSNGGASNIGN- 457
            |..:..|.|.|      |..:.|:...|:.::.    ...||...:.||.:|:....|.|...|
Mosquito   170 PGVLAGLVSGGAGAAGLHHGDGPLGASDLSVQSMSTDSKTGHDDSDQGSLDGDPDCRGDSQAENK 234

  Fly   458 TEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNR 522
            :.||.|    ..|.:..||:....|::.|:..|.:|..|....||:||.:.|||...|||||.|:
Mosquito   235 SPDDGA----GSKRRGPRTTIKAKQLEVLKNAFSQTPKPTRHIREQLAKETGLPMRVIQVWFQNK 295

  Fly   523 RAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLS 587
            |:|.||.::|.:..|.|...||          ..:...|.:||.                 .||.
Mosquito   296 RSKERRLKQLTSMGRGPFFGGA----------RKMRGFPMNLSP-----------------GGLD 333

  Fly   588 SPSTLSTNVNAPTLGAG--IDSSESPTPI-PHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQ 649
            .|       ..|...|.  .|......|. ||..|.                        .|||
Mosquito   334 EP-------GFPYFAADGKFDFGYGGPPFHPHDAPF------------------------FGGH- 366

  Fly   650 NTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGP 714
                             |...|.      .||.....|.| .:.|...:|...|.........||
Mosquito   367 -----------------PGAGPM------PFGGPGGPMDH-PIPMVGDFGMAGPDGGPGGMLGGP 407

  Fly   715 LAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGS 779
            ..|..|....|.                        .:.|.|| |.|...|.|....:|....|.
Mosquito   408 GGPGGPGGGPGG------------------------FMGGPGG-PGGPQQGHGPDGMMGGGVGGG 447

  Fly   780 G 780
            |
Mosquito   448 G 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
AgaP_AGAP011134	XP_309513.3	LIM1_Lhx1_Lhx5	27..78	CDD:188753
		LIM2_Lhx1_Lhx5	86..141	CDD:188761
		Homeobox	247..300	CDD:278475	22/52 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910