DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Cdx4

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_031700.1	Gene:	Cdx4 / 12592	MGIID:	88362	Length:	282	Species:	Mus musculus

Alignment Length:	328	Identity:	81/328 - (24%)
Similarity:	120/328 - (36%)	Gaps:	94/328 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 GTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQ 330
            |||.|         |..||.:|..::.|.||                   |.|.....|||:.
Mouse    16 GTLRS---------PGGSSTAGVGTSGGSGS-------------------PLPASNFTAAPVY-- 50

  Fly   331 SPNHLGTRSSHPQL----VHGNHQALQQHQQQSWPPRH----YSGSWYPTSLSEIPIS------- 380
             |:::|    :|.:    .||  .:|........|||.    |.|.  |:::..:|::
Mouse    51 -PHYVG----YPHMSNMDPHG--PSLGAWSSPYSPPREDWSTYPGP--PSTMGTVPMNDMTSPVF 106

  Fly   381 SAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEG 445
            .:|:. |.....||.|...|| |....|||.|                   ||...|..|.....
Mouse   107 GSPDY-STLGPTSGASNGGSL-PDAASESLVS-------------------LDSGTSGATSPSRS 150

  Fly   446 ENS-----NGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLA 505
            .:|     .......|.|          |..::.|..:|:.|...|||||....|..:..:..||
Mouse   151 RHSPYAWMRKTVQVTGKT----------RTKEKYRVVYTDHQRLELEKEFHCNRYITIRRKSELA 205

  Fly   506 GKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSL 570
            ..:||.|.::::||.|||||.|:  .::.:.....:||.|..|.|.|.:..  :.||:.....|.
Mouse   206 VNLGLSERQVKIWFQNRRAKERK--MIKKKISQFENTGGSVQSDSGSISPG--ELPNAFFTTPSA 266

  Fly   571 LSG 573
            :.|
Mouse   267 VRG 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
Cdx4	NP_031700.1	Caudal_act	13..160	CDD:309740	46/203 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..36		9/28 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	98..156		17/78 (22%)
		Homeobox	175..227	CDD:306543	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910