DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Barhl1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_476450.1	Gene:	Barhl1 / 117232	RGDID:	620648	Length:	327	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	87/353 - (24%)
Similarity:	124/353 - (35%)	Gaps:	102/353 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   312 HAAGPGPLEPARAAPLVG--QSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSL 374
            |.|| .|..| :..||:|  :||..|..||.                                |.
  Rat    15 HRAG-SPALP-KGDPLLGDCRSPLELSPRSE--------------------------------SS 45

  Fly   375 SEIPISSAP------NIASVTAYASGPSLAHSLSPPN---------------------DIESLA- 411
            |:....::|      ...|....||||.|...|.|..                     |.:.||
  Rat    46 SDCSSPASPGRDCLETSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAA 110

  Fly   412 -----SIGHQ-------RNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDD-QA 463
                 |.|..       |....|.||  .:.:||...|..:...|.:....|...|.::.|. ..
  Rat   111 CAPYSSSGQPAAPEPGGRLAAKAGED--FRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPV 173

  Fly   464 RLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR 528
            ||   :|.::.||:||:.|:..||:.|||..|..|..|..||..:.|.:.:::.|:.|||.||:|
  Rat   174 RL---KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKR 235

  Fly   529 EEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLS 593
            :        |.......|.:.:.||...:..||....  .||:|....|.::....|.|:|....
  Rat   236 Q--------TAVGLELLAEAGNYSALQRMFPSPYFYP--QSLVSNLDPGAALYLYRGPSAPPPAL 290

  Fly   594 TNVNAPTL------GAGIDSSESPTPIP 615
            .....|.:      ||    ||.|.|:|
  Rat   291 QRPLVPRILIHGLQGA----SEPPPPLP 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
Barhl1	NP_476450.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..90		24/108 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..181		16/72 (22%)
		Homeobox	182..235	CDD:395001	22/52 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..327		7/16 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910