DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and esx1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_031747349.1	Gene:	esx1 / 116406733	-ID:	-	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	109/404 - (26%)
Similarity:	151/404 - (37%)	Gaps:	133/404 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 PTSLSEIP--ISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELD 433
            ||...:||  |...|.          ..|..:.|||..|  |...|      .||      |..|
Frog    41 PTDKKKIPGNIQQKPQ----------EDLGGAGSPPAKI--LCKTG------TAT------KLRD 81

  Fly   434 GHQSDETGSGEGENSNG-GASNIGNTEDDQARLIL----------------KRKLQRNRTSFTND 481
            |...::..:|..|::.| ..:|....||...:.|.                |||.:|.||:|:|.
Frog    82 GESMEKRLTGVMESTVGVEVANEMCDEDRTGKKIEPVAKQSCALESSAPSGKRKQRRYRTTFSNL 146

  Fly   482 QIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASA 546
            |::.||..|.::||||||.||.||.::.|.|||:||||.|||||||:.||
Frog   147 QLEELEMAFRKSHYPDVFTREDLAMRLDLTEARVQVWFQNRRAKWRKREK--------------- 196

  Fly   547 TSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAP-TLGAGIDSSES 610
                                 :.:|.|.:|.|       :|.|..|..:.|:| |..|......|
Frog   197 ---------------------TEMLGGISGFP-------MSHPLGLYLDGNSPLTDSAWKTVPLS 233

  Fly   611 PTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNF 675
            ..|:|.:.|:.::               ||     .|..|..:|      ...||..  ||.||.
Frog   234 TVPLPSVMPALST---------------SP-----PGSLNLSNI------SWAALFS--SPLLNP 270

  Fly   676 NSGSF-GAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTL 739
            ..|.| |.:...|..::|.|.:      |||: :.|....|..|:    .|:...||:.....:
Frog   271 YFGRFLGVLNPLMTTSSLLMEN------PIPA-SDSDFTALTDPT----MGEWKMSSIAALRQS- 323

  Fly   740 RPPPMAPAHHHIVP 753
                 |..|...||
Frog   324 -----AKEHSEQVP 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	31/51 (61%)
esx1	XP_031747349.1	Homeobox	140..193	CDD:395001	32/52 (62%)
esx1	XP_031747349.1	OAR	311..329	CDD:397759	4/23 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000