DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Prrx2

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001099209.1	Gene:	Prrx2 / 113931	RGDID:	1311471	Length:	248	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	74/215 - (34%)
Similarity:	104/215 - (48%)	Gaps:	39/215 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 SLAHSLSPPNDIESLASIGHQRNCPVATEDIH---LKKELDGHQSDETGSGEGE---NSNGGASN 454
            |::|.|    |:|.:|:.|.:...||...:..   .::...|....|....:||   ..:|.|:.
  Rat    34 SVSHLL----DLEEVAAAGRRAAGPVPGPEAREGAAREPSGGSSGSEAAPQDGECAAPGHGSATK 94

  Fly   455 IGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWF 519
                        .|:|.:||||:|.:.|:.:||:.||||||||.|.||.||.::.|.|||:||||
  Rat    95 ------------RKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWF 147

  Fly   520 SNRRAKWRREEKLRNQRRTPN---STGASATSSSTSATASLTDSPNSL-----SACSSLLSGSAG 576
            .|||||:||.|:.....|:.:   |.|..|......|....|.||:.|     |..||:...|.|
  Rat   148 QNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTLSPDYLSWPASSPYSSVPPYSPG 212

  Fly   577 GPSVSTINGLSSPSTLSTNV 596
            |         |||:|...|:
  Rat   213 G---------SSPATPGVNM 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
Prrx2	NP_001099209.1	Homeobox	104..156	CDD:395001	31/51 (61%)
		COG5576	<110..214	CDD:227863	47/112 (42%)
		OAR	222..238	CDD:397759	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910