DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Prrxl1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_006518472.1	Gene:	Prrxl1 / 107751	MGIID:	2148204	Length:	354	Species:	Mus musculus

Alignment Length:	341	Identity:	100/341 - (29%)
Similarity:	134/341 - (39%)	Gaps:	114/341 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 PVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQID 484
            |.|....|...:|:|            .:..|..:.|:.:|.    .|:||.:||||:||..|::
Mouse    89 PSAMFYFHCPPQLEG------------TAPFGNHSTGDFDDG----FLRRKQRRNRTTFTLQQLE 137

  Fly   485 SLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGAS-ATS 548
            :||..|.:|||||||.||.||.||.|.|||:||||.|||||||:.|:           ||| ...
Mouse   138 ALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTER-----------GASDQEP 191

  Fly   549 SSTSATASLTDSP-----------------NSLSACSSLLSGSAGGPSVSTINGLSSPSTL-STN 595
            .:....|.:|..|                 .:|.|..||  |...||:     |...||.| .|.
Mouse   192 GAKEPMAEVTPPPVRNINSPPPGDQTRSKKEALEAQQSL--GRTVGPT-----GPFFPSCLPGTL 249

  Fly   596 VNAPTLGAGIDSSESPTPIPHIR-----PSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQ 655
            :|..|....:.         |:.     |.|:           |   |.|.|:|: ....|:..|
Mouse   250 LNTATYAQALS---------HVASLKGGPLCS-----------C---CVPDPMGL-SFLPTYGCQ 290

  Fly   656 SNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPL---AP 717
            ||..|...||                .|.:..|..|:..|.:.     :|| ..|:.||.   ||
Mouse   291 SNRTASVAAL----------------RMKAREHSEAVLQSANL-----LPS-TSSSPGPASKQAP 333

  Fly   718 P-------SPIPQQGD 726
            |       ||..:|.:
Mouse   334 PEGSQDKTSPTKEQSE 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	34/51 (67%)
Prrxl1	XP_006518472.1	Homeobox	128..181	CDD:365835	35/52 (67%)
Prrxl1	XP_006518472.1	OAR	292..309	CDD:367680	6/32 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910