DRSC/TRiP Functional Genomics Resources

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Protein Alignment ey and Hoxa2

DIOPT Version :9

Sequence 1:NP_001014693.1 Gene:ey / 43812 FlyBaseID:FBgn0005558 Length:898 Species:Drosophila melanogaster
Sequence 2:NP_036713.2 Gene:Hoxa2 / 103690123 RGDID:2813 Length:372 Species:Rattus norvegicus


Alignment Length:426 Identity:90/426 - (21%)
Similarity:123/426 - (28%) Gaps:205/426 - (48%)


- Green bases have known domain annotations that are detailed below.


  Fly   267 TLSSST----DLMQTATPLNSS----ESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPAR 323
            |||.||    ...||...||..    :|.||....:.|.               |...|...|||
  Rat    41 TLSHSTLIPPPFEQTIPSLNPGSHPRQSAGAGGRPKSSP---------------AGSRGSPVPAR 90

  Fly   324 AAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASV 388
                                       |||       ||             |.|.......|..
  Rat    91 ---------------------------ALQ-------PP-------------EYPWMKEKKAAKK 108

  Fly   389 TAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGAS 453
            ||.   |..|.|..|       |.:||:.:..:|          ||              :||.|
  Rat   109 TAL---PPAAASTGP-------ACLGHKESLEIA----------DG--------------SGGGS 139

  Fly   454 NIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARER---LAGKIGLPEARI 515
                              :|.||::||.|:..|||||   |:.....|.|   :|..:.|.|.::
  Rat   140 ------------------RRLRTAYTNTQLLELEKEF---HFNKYLCRPRRVEIAALLDLTERQV 183

  Fly   516 QVWFSNRRAKWRR----------EEKLRN------------------------------------ 534
            :|||.|||.|.:|          |.|.:|                                    
  Rat   184 KVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSDKVEEDEEEKSLFEQALSVSGALLEREGYTFQ 248

  Fly   535 -----QRRTPNSTGASATSSSTSATASLTDSPNSLS----------ACSSLLSGSAGG------- 577
                 |::.||....   .|.|...:.||.:..:|.          .|.|.:..:.|.       
  Rat   249 QNALSQQQAPNGHNG---DSQTFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSP 310

  Fly   578 -----PSVSTINGLSSPSTLS-TNVNAPTLGAGIDS 607
                 ||:...|..|:.|.|. ::..:|:|...:||
  Rat   311 EALEVPSLQDFNVFSTDSCLQLSDALSPSLPGSLDS 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eyNP_001014693.1 PAX 98..221 CDD:128645
Homeobox 475..527 CDD:278475 23/54 (43%)
Hoxa2NP_036713.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..96 22/115 (19%)
Antp-type hexapeptide 96..101 2/4 (50%)
Homeobox 143..196 CDD:395001 23/55 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..225 4/30 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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