DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and hoxc12

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_002936693.1	Gene:	hoxc12 / 100487557	XenbaseID:	XB-GENE-853677	Length:	263	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	58/252 - (23%)
Similarity:	88/252 - (34%)	Gaps:	48/252 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 LEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRH--YSGSW--------YPTS 373
            |.|....|||.   .|.|.....|.......| |......|:|.|.  .|..|        ||..
Frog     7 LNPGFVGPLVN---IHTGDTFYFPNFRTPGGQ-LPGLPSLSYPRRENVCSLPWASTEPCNGYPQP 67

  Fly   374 LSEIPISSAP------NIASVTA----YASG-----PSLAHS---LSPPNDIESLASIGHQRNCP 420
            ....|:|..|      ::|.|..    |..|     |||...   |...:.|.|..:...|:...
Frog    68 YLSSPVSINPSFSRACDLARVEETKCYYREGCNPDTPSLKRENVLLPLESGIHSAMNSTFQKYDY 132

  Fly   421 VATEDIHLKKELDGHQSDETGSGEGENSNG------------GASNIGNT--EDDQARLILKRKL 471
            .|.:.:  ..:....||.|:.||....:.|            ..||.||:  ........:..:.
Frog   133 TAVDSV--PHDPPSCQSLESDSGSSLLNEGTKNAVSEAATMASPSNPGNSLPASGAPWYPIHTRS 195

  Fly   472 QRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR 528
            ::.|..::..|:..||.||....:.....|..|:.::.|.:.::::||.|||.|.:|
Frog   196 RKKRKPYSKIQLAELEGEFMVNEFITRQRRRELSDRLSLSDQQVKIWFQNRRMKKKR 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	15/51 (29%)
hoxc12	XP_002936693.1	Homeobox	198..252	CDD:365835	15/53 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910