DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and hoxc13

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_002936691.1	Gene:	hoxc13 / 100487255	XenbaseID:	XB-GENE-478832	Length:	306	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	72/336 - (21%)
Similarity:	122/336 - (36%)	Gaps:	99/336 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 NSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRL 307
            |..:.:.|.::.|...|.||      |...|.:       |..:.|..:|..||.|..:|..
Frog    24 NEKNPRKSPAMEGLSGNCAS------SHCRDFI-------SHPALGRHSSAIGSHQGPVYTD--- 72

  Fly   308 LNTQHAAGPGPLEPARAAPLVGQS----PNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGS 368
            :.:..||......|:.:...:|.:    .::.|.|.|....|:       .||:   |..::...
Frog    73 ITSPEAARQCTAPPSSSNASLGYAYPFGSSYYGCRLSQSHNVN-------LHQK---PCSYHPAE 127

  Fly   369 WYPTSLSEIP----ISSAPNIASVTAYASG-------------PSLAHSLSPPNDIESLASI-GH 415
            .||...:.:|    .|.|...|...::||.             |.::....|.:|  :|.|: |:
Frog   128 KYPEPSNPLPSEEFSSRAKEFAFYPSFASSYQAVPGYLDMSVVPGISSHPEPRHD--TLLSMEGY 190

  Fly   416 QRNCPVATEDIH--LKKELDGH---QSDETGSG-------------EGENSNGGASNIGNTEDDQ 462
            |          |  |....||.   ..|::.||             :.|.||
Frog   191 Q----------HWALPNGWDGQVYCSKDQSQSGHLWKAPFPDVVPLQPEVSN------------- 232

  Fly   463 ARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWR 527
                 .|:.::.|..:|..|:..||||:..:.:.....|.|::....|.|.::.:||.|||.|
Frog   233 -----YRRGRKKRVPYTKIQLKELEKEYAASKFITKEKRRRISTATSLSERQVTIWFQNRRVK-- 290

  Fly   528 REEKLRNQRRT 538
             |:|:..:.:|
Frog   291 -EKKVVTKCKT 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	17/51 (33%)
hoxc13	XP_002936691.1	HoxA13_N	31..142	CDD:372013	28/136 (21%)
hoxc13	XP_002936691.1	Homeobox	239..293	CDD:365835	18/56 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910