DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and phox2a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001239128.1	Gene:	phox2a / 100486496	XenbaseID:	XB-GENE-853857	Length:	281	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	81/249 - (32%)
Similarity:	110/249 - (44%)	Gaps:	55/249 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 TAYASGPSLAHSLSPPNDIE---SLASIGHQRNCPVATEDIHLKKELDGHQ------------SD 438
            :|||.    ..|.|.||..:   ...|.|....||..|........|..||            ||
Frog    22 SAYAD----FSSCSQPNSFQYNPIRGSFGANPACPPLTTANCTLGALRDHQPSPYSTVPYKFFSD 82

  Fly   439 ETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARER 503
            .:|..|                       |||.:|.||:||:.|:..||:.|..|||||::.||.
Frog    83 PSGINE-----------------------KRKQRRIRTTFTSSQLKELERVFAETHYPDIYTREE 124

  Fly   504 LAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACS 568
            ||.||.|.|||:||||.|||||:|::|:..|.:...::.|.|....|...::| .|..:..|.||
Frog   125 LALKIDLTEARVQVWFQNRRAKFRKQERAANSKSGSSNNGGSGNKKSDPRSSS-EDDESKESNCS 188

  Fly   569 SLLSGSAGGPSVSTIN----GLS-SPSTLSTNVNAPTLGA-------GIDSSES 610
            .....:|..|:...:|    .|| ||..:|..|:|.|:.|       |:.:|.|
Frog   189 PTPDSTASLPTAGNLNSPGGSLSPSPGAVSGLVSAHTVQALKGPAWPGVPTSSS 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
phox2a	NP_001239128.1	Homeobox	96..148	CDD:278475	32/51 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000