DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and shox

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_004911874.1	Gene:	shox / 100486480	XenbaseID:	XB-GENE-920752	Length:	334	Species:	Xenopus tropicalis

Alignment Length:	155	Identity:	54/155 - (34%)
Similarity:	85/155 - (54%)	Gaps:	31/155 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 TAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGAS 453
            |..|....|.:|.:...||...::     :||     :||.||   |.:|   |.:.:..:.|::
Frog    79 TGLARVRELGNSETNLQDITDTSN-----HCP-----LHLYKE---HGAD---SDKDKLKDYGST 127

  Fly   454 NIG-------------NTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLA 505
            .:.             .:||:..:..||::  |:||:||.:|::.||:.|:.|||||.|.||.|:
Frog   128 RVSEGIYECKEKRDDVKSEDEDGQTKLKQR--RSRTNFTLEQLNELERLFDETHYPDAFMREELS 190

  Fly   506 GKIGLPEARIQVWFSNRRAKWRREE 530
            .::||.|||:||||.|||||.|::|
Frog   191 QRLGLSEARVQVWFQNRRAKCRKQE 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	31/51 (61%)
shox	XP_004911874.1	Homeobox	159..213	CDD:365835	31/53 (58%)
shox	XP_004911874.1	OAR	314..330	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910