DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and pax9

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_002935394.1	Gene:	pax9 / 100485934	XenbaseID:	XB-GENE-482238	Length:	360	Species:	Xenopus tropicalis

Alignment Length:	391	Identity:	140/391 - (35%)
Similarity:	187/391 - (47%)	Gaps:	94/391 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 VNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIG 165
            |||||||||.|||||::.|.:|||||..|.|||||||.|:||:|||||||.||.|||||.|.|||
Frog     8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIG 72

  Fly   166 GSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLR----NLAAQ 226
            ||||||.|..||..|..||:..|.|||||||||||.:.||...|:||||||:|:||    |||.|
Frog    73 GSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQ 137

  Fly   227 KEQQSTGSGSSSTSA---------GNSISAKVSV-------SIGGNV--------SNVASGSRGT 267
            ...:|.....::.||         .:.|:|...|       ||.|.:        |:..:...|
Frog   138 NHYESHKQHPAAASALPYNHLYSYPSPIAAGAKVPTPPGMPSIPGTMGMPRTWPSSHSVTDILG- 201

  Fly   268 LSSSTDLMQTATP-----------LNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEP 321
            :.|.||.:...:|           |:.:....|.:...|.|:.::.::::.  :|.|:|...:..
Frog   202 IRSITDQVSDTSPYPSPKLEEWSSLSRNTFQSAQHVLNGLEKSSLEQEVKY--SQSASGLPAVSG 264

  Fly   322 ARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPIS--SAPN 384
            ..||.  |.:|                                     |||:   .|:|  .|.:
Frog   265 FVAAS--GMTP-------------------------------------YPTT---APVSPYMAYS 287

  Fly   385 IASVTAYASGPSLAHS----LSPPN-DI-ESLASIGHQ--RNCPVATEDIHLKKELDGHQSDETG 441
            .|:.|.|.:|....|:    |||.: || .|||..|..  |....:...||.:|....:.:...|
Frog   288 TAAPTGYVTGHGWQHTGGTPLSPHSCDITASLAFKGMHTAREAEESKLSIHTRKSPQSYHTQRHG 352

  Fly   442 S 442
            :
Frog   353 T 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	83/119 (70%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475
pax9	XP_002935394.1	PAX	6..131	CDD:238076	85/122 (70%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910