Sequence 1: | NP_001014693.1 | Gene: | ey / 43812 | FlyBaseID: | FBgn0005558 | Length: | 898 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001280727.1 | Gene: | DUX4 / 100288687 | HGNCID: | 50800 | Length: | 424 | Species: | Homo sapiens |
Alignment Length: | 402 | Identity: | 105/402 - (26%) |
---|---|---|---|
Similarity: | 143/402 - (35%) | Gaps: | 95/402 - (23%) |
- Green bases have known domain annotations that are detailed below.
Fly 472 QRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAK----WRREEKL 532
Fly 533 RNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVN 597
Fly 598 APTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQ-SNGHAQ 661
Fly 662 GHALVPAISPRLNFNSGSF--GAMYSNMHHTALSMSDSY-----GAVTPIPSFNHSAVGPLAPPS 719
Fly 720 PIPQQGDLT--PSSLYPCHMTLR-----------PPPMAPAHHHIVPGDG-GRPAGVGL------ 764
Fly 765 ------GSGQSANLGASCSGSGYEVLSAYALPP---PPMASSSAADSSFSAASSASANVTPHHTI 820
Fly 821 AQESCP---SPC 829 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ey | NP_001014693.1 | PAX | 98..221 | CDD:128645 | |
Homeobox | 475..527 | CDD:278475 | 24/55 (44%) | ||
DUX4 | NP_001280727.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..24 | 1/3 (33%) | |
Homeobox | 27..74 | CDD:306543 | 23/46 (50%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 72..102 | 7/29 (24%) | |||
Homeobox | 97..149 | CDD:306543 | 13/77 (17%) | ||
DNA_pol3_gamma3 | <141..319 | CDD:331207 | 44/195 (23%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 218..362 | 38/163 (23%) | |||
Required for interaction with EP300 and CREBBP, and for transcriptional activation of target genes. /evidence=ECO:0000269|PubMed:26951377 | 327..424 | 15/51 (29%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 388..414 | ||||
Important for transcriptional activation of target genes. /evidence=ECO:0000269|PubMed:29618456 | 405..424 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0849 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |