DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and mxtx1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571635.2	Gene:	mxtx1 / 100149566	ZFINID:	ZDB-GENE-000710-7	Length:	309	Species:	Danio rerio

Alignment Length:	313	Identity:	71/313 - (22%)
Similarity:	104/313 - (33%)	Gaps:	110/313 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   438 DETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARE 502
            |.|.....:.|..||             :.:...:|.||||:.:.::.|...||...||.:..||
Zfish     4 DSTIDATAKTSGSGA-------------VSRSASRRKRTSFSKEHVELLRATFETDPYPGISLRE 55

  Fly   503 RLAGKIGLPEARIQVWFSNRRAK-----------WRREEKLRNQRRTPNSTGASATSSSTSATAS 556
            .|:...||||:||||||.||||:           |:.:....|..:|.........:.|:.||.:
Zfish    56 SLSQTTGLPESRIQVWFQNRRARTLKCKGGKKPLWQTDLPAYNNMQTSPMQIHRKNNESSGATGT 120

  Fly   557 LTDSPNSLSACSSLLSGSAGGPSV----------STINGLSSPSTLSTNVNAPTLGAGIDSSESP 611
            |...|                |:.          ..:.|..:||::|.:          |.|...
Zfish   121 LCSPP----------------PAYPDRIKEEMEKDAVCGCDTPSSMSIS----------DDSGYC 159

  Fly   612 TPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFN 676
            ||..|             ||...:...||.||....||                   :.|.....
Zfish   160 TPSYH-------------QSRAIQSHMSPSPLLSPEHQ-------------------MPPNWGVR 192

  Fly   677 SG---SFGAMYSNMHHTALSMSDSYGAVTPIPSF------NHSAVGPLAPPSP 720
            .|   ...:|:|..|..|.:.:         |.|      .|:.:.||.|.:|
Zfish   193 YGRRSPMSSMWSPYHLEAYACN---------PGFFYSHSEKHNTLQPLTPVTP 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	26/62 (42%)
mxtx1	NP_571635.2	HOX	24..78	CDD:197696	26/53 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810