Protein Alignment ey and phox2b

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001116492.1
• Gene: phox2b / 100124329
• XenbaseID: XB-GENE-1000415
• Length: 293
• Species: Xenopus tropicalis
• Alignment Length: 350
• Identity: 94/350 - (26%)
• Similarity: 128/350 - (36%)
• Gaps: 106/350 - (30%)

  Fly   406 DIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENS-----NGGASNIGNTED----- 460
            |..||||         |..|.....:..|.|.:...:..|..|     ..|:.::|...|
 Frog    22 DTSSLAS---------AYADFSSCSQASGFQYNPIRTTFGATSGCPSLTPGSCSLGTLRDHQSSP 77

  Fly   461 ----------DQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARI 515
                      |...|..|||.:|.||:||:.|:..||:.|..|||||::.||.||.||.|.|||:
 Frog    78 YAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARV 142

  Fly   516 QVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSV 580
            ||||.|||||:|::|:...........|:|...|.:|......||       .|....|.|||.
 Frog   143 QVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDEESKDS-------KSADPDSTGGPG- 199

  Fly   581 STINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGV 645
                  ::|:.      .|:.|.|              ||.:....||...|       |..:||
 Frog   200 ------NNPNP------TPSCGGG--------------PSPSGAQGNGVPQE-------PGKVGV 231

  Fly   646 ---GGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSF 707
               |...:...:..:|..||.|..|.                              |.:|.||.
 Frog   232 PGPGSLTSASVVGVSGGPQGWATGPG------------------------------GTITSIPD- 265

  Fly   708 NHSAVGPLAPPSPIPQQGDLTPSSL 732
              |..||.|......|:.:.|.::|
 Frog   266 --SLGGPFASVLSSLQRPNSTKATL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
		Homeodomain	473..528	CDD:459649	33/54 (61%)
phox2b	NP_001116492.1	Homeodomain	99..155	CDD:459649	33/55 (60%)