Protein Alignment myo and Bmp7

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_001178785.1
• Gene: Bmp7 / 85272
• RGDID: 620743
• Length: 430
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 113/503 - (22%)
• Similarity: 189/503 - (37%)
• Gaps: 149/503 - (29%)

  Fly   165 LAKVSEHGDLSRVQSVSLYRNTLINI-------ESMLQRQLREKAKVDSIESIKMHILMRLNLKK 222
            |...:.|..::....:.|.|:.|.:.       .|.:.|:||.:.:.:....|       |::..
  Rat     6 LRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREI-------LSILG 63

  Fly   223 LPNITKP------ISVPQNIIDNFYRDYNASSKTTVWNRMESIDES----------HLSINDTYG 271
            ||:..:|      .|.|..::|             ::|.| :::||          :.::..|.|
  Rat    64 LPHRPRPHLQGKHNSAPMFMLD-------------LYNAM-AVEESGPDGQGFSYPYKAVFSTQG 114

  Fly   272 --------DHIMTDFFDESSSSQMQGDDANTV-------------NEFLIDLNKNQAKKSDIPIN 315
                    .|.:||       :.|.....|.|             .||..||:|       ||
  Rat   115 PPLASLQDSHFLTD-------ADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSK-------IP-- 163

  Fly   316 TNDEEYESILSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAH 380
                |.|::.:....||      :.::|.....:.|:..:.....:.|.....|:|.....|.|.
  Rat   164 ----EGEAVTAAEFRIY------KDYIRERFDNETFQITVYQVLQEHSGRESDLFLLDSRTIWAS 218

  Fly   381 QPGLLEEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGL--------GQWVAVDL 437
            :.|.|.       .||..|       :|....||       ||::  ||        ||.:...|
  Rat   219 EEGWLV-------FDITAT-------SNHWVVNP-------RHNL--GLQLSVETLDGQSINPKL 260

  Fly   438 KSLLGNLGSNMTQEILI---KGAETWMKSLVVT-----TDNTSKNPLTVHIEIGSQKKHRRKRSV 494
            ..|:|..|....|..::   |..|..::|:..|     :.|.||.|        ..::..|..||
  Rat   261 AGLIGRHGPQNKQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTP--------KNQEALRMASV 317

  Fly   495 YMDCTENDHDMRCCRYPLKVNFTSFGWH-FVVAPTSFDAYFCSGDCKV---GYLEQYPH------ 549
             .:.:.:|....|.::.|.|:|...||. :::||..:.||:|.|:|..   .|:....|
  Rat   318 -AENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTL 381

  Fly   550 THLAALTTSATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSC 597
            .|.....|...|||:||:::::|:|||||:.|::|....||.|..|.|
  Rat   382 VHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	34/100 (34%)
Bmp7	NP_001178785.1	TGFb_propeptide	35..279	CDD:459906	61/313 (19%)
		TGF_beta_BMP7	324..430	CDD:381667	36/106 (34%)