Protein Alignment myo and Tgfb2

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_112393.2
• Gene: Tgfb2 / 81809
• RGDID: 70491
• Length: 442
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 109/493 - (22%)
• Similarity: 183/493 - (37%)
• Gaps: 141/493 - (28%)

  Fly   179 SVSLYRNTLINIESMLQRQLREKAKVDSIESIKMHILMRLNLKKLP-NITKPISVPQNIID--NF 240
            ::||...:.::::..::::         ||:|:..||.:|.|...| :..:|..||..:|.  |.
  Rat    18 ALSLSTCSTLDMDQFMRKR---------IEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISIYNS 73

  Fly   241 YRDY---NASSKTTVWNRMESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDL 302
            .||.   .||.:.....| |..||.:      |...:                       :.||:
  Rat    74 TRDLLQEKASRRAAACER-ERSDEEY------YAKEV-----------------------YKIDM 108

  Fly   303 NKNQAKKSDIP-INTNDEEYESILSHISSIY------IFPEEIQPHVRHNRKVDVFRFQI---DS 357
            ..:...::..| :.|:.....|..|..|.:.      |.|...:|:.|      :.||.:   :.
  Rat   109 PSHFPSETVCPVVTTSSGSVGSFCSRQSQVLCGYLDAIPPTFYRPYFR------IVRFDVSTMEK 167

  Fly   358 SYSDLSYATLHLY-LRGWDWISAHQPGLLEEIKKQPRKDIVVTIHRAI--RVANTTSFNPKVKMF 419
            :.|:|..|...:: |:......|.|...|.:|.|.  ||:.....|.|  :|..|.:
  Rat   168 NASNLVKAEFRVFRLQNPKARVAEQRIELYQILKS--KDLTSPTQRYIDSKVVKTRA-------- 222

  Fly   420 EFRHSIPSGLGQWVAVDLKSLL--------GNLG--------------------SNMTQEIL--- 453
                     .|:|::.|:...:        .|||                    .|.:||:.
  Rat   223 ---------EGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARF 278

  Fly   454 --IKGAETWMKSLVVTTDNTSK--NPLTVHIEI---------GSQKKHRRKRSVYMD---CTEND 502
              |.|..|:......|..:|.|  :..|.|:.:         ..|...||||:  :|   |..|.
  Rat   279 AGIDGTSTYASGDQKTIKSTRKKSSGKTPHLLLMLLPSYRLESQQSSRRRKRA--LDAAYCFRNV 341

  Fly   503 HDMRCCRYPLKVNF-TSFGWHFVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAAL------TTSAT 560
            .| .||..||.::| ...||.::..|..::|.||:|.|...:.....||.:.:|      ..||:
  Rat   342 QD-NCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASAS 405

  Fly   561 PCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            |||....:..|::||:..| ...:..:.||.|:.|.||
  Rat   406 PCCVSQDLEPLTILYYIGN-TPKIEQLSNMIVKSCKCS 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	29/97 (30%)
Tgfb2	NP_112393.2	TGFb_propeptide	21..256	CDD:459906	57/298 (19%)
		TGF_beta_TGFB2	345..441	CDD:381655	29/96 (30%)