Protein Alignment myo and LEFTY2

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_003231.2
• Gene: LEFTY2 / 7044
• HGNCID: 3122
• Length: 366
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 80/385 - (20%)
• Similarity: 133/385 - (34%)
• Gaps: 118/385 - (30%)

  Fly   287 MQGDDANTVNEFLIDLNKNQAKKSDIPI-NTNDEEYESILSHISSIYIFPEEIQPHVRHNRKVDV 350
            :.|..|....|.|:.....|.:.|::|: :..|.|...|.:|:.:.|:    :.....|..:...
Human    15 LAGPGAALTEEQLLGSLLRQLQLSEVPVLDRADMEKLVIPAHVRAQYV----VLLRRSHGDRSRG 75

  Fly   351 FRFQIDSSYSDL------SYATLHLYLRGWDWISAHQPGLLEEIKKQPRKDIVVTIHRAIRVANT 409
            .||  ..|:.::      |.|:.||.:.|.            |.:..|..::|..:.|..:
Human    76 KRF--SQSFREVAGRFLASEASTHLLVFGM------------EQRLPPNSELVQAVLRLFQ---- 122

  Fly   410 TSFNPKVKMFEFRHSIPSGLGQWVAVDLKSL-LGNLGSNMTQEI---LIKGAETWMKSLVVTTD- 469
               .|..|....||...|.......|.::.| :.:.|||.|..|   |:...|:..|:..||..
Human   123 ---EPVPKAALHRHGRLSPRSAQARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDVTEAV 184

  Fly   470 ------NTSKNPLTVHIEIGSQKKH----------------------------------RRKRSV 494
                  :..:.||.:.:.:  |::|                                  .|....
Human   185 NFWQQLSRPRQPLLLQVSV--QREHLGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLRDYGA 247

  Fly   495 YMDC------TENDHDMRCCRYPLKVNFTSFGW--HFVVAPTSFDAYFCSGDCKVGYLEQYPHTH 551
            ..||      ||.   .||||..:.::.....|  ::|:.|..|.||.|.|.|      |.|...
Human   248 QGDCDPEAPMTEG---TRCCRQEMYIDLQGMKWAKNWVLEPPGFLAYECVGTC------QQPPEA 303

  Fly   552 LAALTTSATP-CCSPTKMSSLSLLYFDDNHNLVLSV------------IPNMSVEGCSCS 598
            ||.......| .|..::.:||.         :::|:            :|||.|:.|||:
Human   304 LAFNWPFLGPRQCIASETASLP---------MIVSIKEGGRTRPQVVSLPNMRVQKCSCA 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	27/105 (26%)
LEFTY2	NP_003231.2	TGFb_propeptide	<106..214	CDD:307025	24/116 (21%)
		TGF_beta	263..353	CDD:306518	26/104 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010