Protein Alignment myo and TGFB3

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_001316868.1
• Gene: TGFB3 / 7043
• HGNCID: 11769
• Length: 412
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 97/482 - (20%)
• Similarity: 156/482 - (32%)
• Gaps: 191/482 - (39%)

  Fly   203 KVDSIESIKMHILMRLNLKKLPNITKPISVPQNIIDNFYRDYNASSKTTVWNRMESIDESHLSIN 267
            |...:|:|:..||.:|.|...|..|....||..::    ..||::        .|.::|.|
Human    36 KKKRVEAIRGQILSKLRLTSPPEPTVMTHVPYQVL----ALYNST--------RELLEEMH---- 84

  Fly   268 DTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEEYESILSHISSIY 332
               |:.      :|..:.:                            ||..|.|      ...|:
Human    85 ---GER------EEGCTQE----------------------------NTESEYY------AKEIH 106

  Fly   333 IFPEEIQPHVRHNRKV--------DVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLLEEIK 389
            .| :.||....||...        .||||.:.|                              ::
Human   107 KF-DMIQGLAEHNELAVCPKGITSKVFRFNVSS------------------------------VE 140

  Fly   390 KQPRKDIVVTIHRAIRVANTTS--FNPKVKMFEF----RH----------SIPS-GLGQWVAVDL 437
            |. |.::.....|.:||.|.:|  ...::::|:.    .|          ::|: |..:|::.|:
Human   141 KN-RTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204

  Fly   438 KSLL--------GNLGSNMT---------------------QEILIKGAETWMKSLVVTTDNTSK 473
            ...:        .|||..::                     .||..||.:        ..|:..:
Human   205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVD--------NEDDHGR 261

  Fly   474 NPLTVHIEIGSQKKH-----------------------RRKRSVYMDCTENDHDMRCCRYPLKVN 515
            ..|.   .:..||.|                       |:||::..:....:.:..||..||.::
Human   262 GDLG---RLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYID 323

  Fly   516 F-TSFGWHFVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAAL--------TTSATPCCSPTKMSSL 571
            | ...||.:|..|..:.|.||||.|.  ||.....||...|        ..||:|||.|..:..|
Human   324 FRQDLGWKWVHEPKGYYANFCSGPCP--YLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPL 386

  Fly   572 SLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            ::||:......| ..:.||.|:.|.||
Human   387 TILYYVGRTPKV-EQLSNMVVKSCKCS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	34/99 (34%)
TGFB3	NP_001316868.1	TGFb_propeptide	24..230	CDD:395559	49/284 (17%)
		Cell attachment site. /evidence=ECO:0000250|UniProtKB:P01137	261..263		0/1 (0%)
		TGF_beta_TGFB3	312..412	CDD:381656	34/102 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010