Protein Alignment myo and TGFB2

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_001129071.1
• Gene: TGFB2 / 7042
• HGNCID: 11768
• Length: 442
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 100/488 - (20%)
• Similarity: 189/488 - (38%)
• Gaps: 131/488 - (26%)

  Fly   179 SVSLYRNTLINIESMLQRQLREKAKVDSIESIKMHILMRLNLKKLP-NITKPISVPQNIID--NF 240
            ::||...:.::::..::::         ||:|:..||.:|.|...| :..:|..||..:|.  |.
Human    18 ALSLSTCSTLDMDQFMRKR---------IEAIRGQILSKLKLTSPPEDYPEPEEVPPEVISIYNS 73

  Fly   241 YRDY---NASSKTTVWNRMESIDESHLSINDTYGDHI----MTDFFDESSSSQMQGDDANTVNEF 298
            .||.   .||.:.....| |..||.:      |...:    |..||...:...:....:.:|...
Human    74 TRDLLQEKASRRAAACER-ERSDEEY------YAKEVYKIDMPPFFPSETVCPVVTTPSGSVGSL 131

  Fly   299 LIDLNKNQAKKSDIPINTNDEEYESILSHISSIYIFPEEIQPHVRHNRKVDVFRFQI---DSSYS 360
            .       :::|.:           :..::.:|.  |...:|:.|      :.||.:   :.:.|
Human   132 C-------SRQSQV-----------LCGYLDAIP--PTFYRPYFR------IVRFDVSAMEKNAS 170

  Fly   361 DLSYATLHLYLRGWDWISAHQPGLLEEIK-KQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHS 424
            :|..|...::             .|:..| :.|.:.|  .:::.::..:.||  |..:..:.:..
Human   171 NLVKAEFRVF-------------RLQNPKARVPEQRI--ELYQILKSKDLTS--PTQRYIDSKVV 218

  Fly   425 IPSGLGQWVAVDLKSLL--------GNLG--------------------SNMTQEIL-----IKG 456
            .....|:|::.|:...:        .|||                    .|.::|:.     |.|
Human   219 KTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDG 283

  Fly   457 AETW----MKSLVVT-TDNTSKNP-----LTVHIEIGSQKKHRRKR----SVYMDCTENDHDMRC 507
            ..|:    .|::..| ..|:.|.|     |.....:.||:.:|||:    :.|  |..|..| .|
Human   284 TSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAY--CFRNVQD-NC 345

  Fly   508 CRYPLKVNF-TSFGWHFVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAAL------TTSATPCCSP 565
            |..||.::| ...||.::..|..::|.||:|.|...:.....|:.:.:|      ..||:|||..
Human   346 CLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVS 410

  Fly   566 TKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            ..:..|::||: ......:..:.||.|:.|.||
Human   411 QDLEPLTILYY-IGKTPKIEQLSNMIVKSCKCS 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	27/97 (28%)
TGFB2	NP_001129071.1	TGFb_propeptide	21..256	CDD:395559	50/293 (17%)
		TGF_beta_TGFB2	345..441	CDD:381655	27/96 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010