Protein Alignment myo and TGFB1

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: XP_011525544.1
• Gene: TGFB1 / 7040
• HGNCID: 11766
• Length: 391
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 83/451 - (18%)
• Similarity: 147/451 - (32%)
• Gaps: 150/451 - (33%)

  Fly   200 EKAKVDSIESIKMHILMRLNLKKLPN--ITKPISVPQNIIDNFYRDYNASSKTTVWNRMESIDES 262
            |..|...||:|:..||.:|.|...|:  ...|..:|:.::             .::|
Human    39 ELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVL-------------ALYN-------- 82

  Fly   263 HLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEEYESILSH 327
                               |:..::.|:.|....|...|....:..:. :.:.|::|.|:.....
Human    83 -------------------STRDRVAGESAEPEPEPEADYYAKEVTRV-LMVETHNEIYDKFKQS 127

  Fly   328 ISSIYIF----------PEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQP 382
            ..|||:|          ||.:.                      ||.|.|.| ||
Human   128 THSIYMFFNTSELREAVPEPVL----------------------LSRAELRL-LR---------- 159

  Fly   383 GLLEEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLGNLGSN 447
                         :.:.:.:.:.:....| |...:....|...||...:|::.|:        :.
Human   160 -------------LKLKVEQHVELYQKYS-NNSWRYLSNRLLAPSDSPEWLSFDV--------TG 202

  Fly   448 MTQEILIKGAET--WMKSLVVTTDNTSKNPLTVHIEIG--------------------------- 483
            :.::.|.:|.|.  :..|...:.|:.. |.|.|.|..|
Human   203 VVRQWLSRGGEIEGFRLSAHCSCDSRD-NTLQVDINAGFTTGRRGDLATIHGMNRPFLLLMATPL 266

  Fly   484 SQKKH----RRKRSVYMDCTENDHDMRCCRYPLKVNF-TSFGWHFVVAPTSFDAYFCSGDCKVGY 543
            .:.:|    |.:|::..:...:..:..||...|.::| ...||.::..|..:.|.||.|.|...:
Human   267 ERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIW 331

  Fly   544 LEQYPHTHLAAL------TTSATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            .....::.:.||      ..||.|||.|..:..|.::|:......| ..:.||.|..|.||
Human   332 SLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKV-EQLSNMIVRSCKCS 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	27/97 (28%)
TGFB1	XP_011525544.1	TGFb_propeptide	30..262	CDD:395559	51/319 (16%)
		TGF_beta_TGFB1	293..391	CDD:381654	27/98 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010