Protein Alignment myo and BMP8B

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: XP_011540326.2
• Gene: BMP8B / 656
• HGNCID: 1075
• Length: 427
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 101/457 - (22%)
• Similarity: 167/457 - (36%)
• Gaps: 117/457 - (25%)

  Fly   195 QRQLREKAKVDSIESIKMHILMRLNLKKLPNITKPISVPQNIIDNFYRDYNASSKTTVWNRMESI 259
            ||:|..:.:.|    ::..||..|.   ||...:|.:.|            |:|:......:..:
Human    33 QRRLGARERRD----VQREILAVLG---LPGRPRPRAPP------------AASRLPASAPLFML 78

  Fly   260 DESHLSINDTYGD-----------HIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIP 313
            |..|....|...|           .::..|.:.....:..|.......||..||       :.||
Human    79 DLYHAMAGDDDEDGAPAERRLGRADLVMSFVNMVERDRALGHQEPHWKEFRFDL-------TQIP 136

  Fly   314 INTNDEEYESILSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSD-------LSYATLHLYL 371
            ........|..:..:.||::.          ||.:.|..||:....|:       |...||....
Human   137 AGEAVTAAEFRIYKVPSIHLL----------NRTLHVSMFQVVQEQSNRESDLFFLDLQTLRAGD 191

  Fly   372 RGW---DWISAHQPGLLEEIKKQPRKDIVVTIHRAIRVANT-TSF----NPKVKMFEFRHS-IPS 427
            .||   |..:|....||:.     .||:.:.::.......| |.:    :.:::|::.|.| .|
Human   192 EGWLVLDVTAASDCWLLKR-----HKDLGLRLYVETEDGETWTGWGWTKDSRLQMWKLRLSRTP- 250

  Fly   428 GLGQWVAVDLKSLLGNLGSNMTQEILIKGAETWMKSLVVTTDNTSKNPLTVHIEIGSQKKHRRKR 492
                ||       |........|    ..||..:..|:......|.:|:.....:...::.:.|:
Human   251 ----WV-------LSLHAPGPAQ----APAERPLLCLLQGHCPASPSPIRTPRAVRPLRRRQPKK 300

  Fly   493 SVYM----------DCTENDHDMRCC-RYPLKVNFTSFGW-HFVVAPTSFDAYFCSGDCKVGYLE 545
            |..:          |.....|..:.| |:.|.|:|...|| .:|:||..:.||:|.|:|
Human   301 SNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGEC------ 359

  Fly   546 QYP---------HTHLAALTTSATP------CCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGC 595
            .:|         |..|.:|.....|      ||:|||:|:.|:||:|.::|::|....||.|:.|
Human   360 SFPLDSCMNATNHAILQSLVHLMMPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKAC 424

  Fly   596 SC 597
            .|
Human   425 GC 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	36/107 (34%)
BMP8B	XP_011540326.2	TGFb_propeptide	33..226	CDD:459906	45/233 (19%)
		TGF_beta_BMP8	323..427	CDD:381668	37/110 (34%)