DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment myo and Inhbc

DIOPT Version :9

Sequence 1:	NP_726604.1	Gene:	myo / 43811	FlyBaseID:	FBgn0026199	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_072136.1	Gene:	Inhbc / 64549	RGDID:	621194	Length:	351	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	86/414 - (20%)
Similarity:	153/414 - (36%)	Gaps:	128/414 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 IESIKMHILMRLNLKKLPNITKPISVPQNIIDNFYRDYNASSKTTVWNRMESIDESHLSINDTYG 271
            ::..|..||.:|:|.:.|.:::|:|              ..:..|...|:.......|..:|...
  Rat    44 LDLAKKSILDKLHLSQRPILSRPVS--------------REALKTALRRLRGTRAETLLEHDQRQ 94

  Fly   272 DHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEEYESILSHISSIYIFPE 336
            ::.:..|.|...|:         :|:..::.:.:......:.:             :.:.::|..
  Rat    95 EYEIISFADTGLSN---------INQTRLEFHFSDRTTGGVEV-------------LQTRFMFFM 137

  Fly   337 EIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLLEEIKKQPRKDIVVTIH 401
            ::.|:......:.|                  |.||.:|                  .::.:|..
  Rat   138 QLPPNTTQTMNIRV------------------LVLRPYD------------------TNLTLTSQ 166

  Fly   402 RAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLGNLG------SNMTQEILIKGAETW 460
            ..::|.                  .||   |..:    |||...      .::|.| |:..::..
  Rat   167 YMLQVD------------------ASG---WYQL----LLGPEAQAACSQGHLTLE-LVPESQLA 205

  Fly   461 MKSLVVTTDNTSKNPLTVHIEIGSQKKHR-RKRSVYMDCTENDHDMRCCRYPLKVNFTSFGWH-F 523
            ..||::  |..|..|. |..::..:.||| |:|.:  :|  ......|||....|:|...||| :
  Rat   206 HSSLIL--DGVSHRPF-VAAQVRVEGKHRVRRRGI--NC--QGLSRMCCRQEFFVDFREIGWHDW 263

  Fly   524 VVAPTSFDAYFCSGDCKVGYLEQYP------HTH----LAALTTSAT----PCCSPTKMSSLSLL 574
            ::.|..:...||:|.|.: ::...|      ||.    |.|.|.:.|    .||.||....||||
  Rat   264 IIQPEGYAMNFCTGQCPL-HVAGMPGISASFHTAVLNLLKANTDAGTARRGSCCVPTSRRPLSLL 327

  Fly   575 YFDDNHNLVLSVIPNMSVEGCSCS 598
            |:|.:.|:|.:.||:|.||.|.||
  Rat   328 YYDRDSNIVKTDIPDMVVEACGCS 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	38/105 (36%)
Inhbc	NP_072136.1	TGF_beta_INHBC_E	246..351	CDD:381676	38/105 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010