Protein Alignment myo and NODAL

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_060525.3
• Gene: NODAL / 4838
• HGNCID: 7865
• Length: 347
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 79/334 - (23%)
• Similarity: 124/334 - (37%)
• Gaps: 85/334 - (25%)

  Fly   323 SILSHISSIYIFPEEIQPHVRHNRKVDV----------FRFQIDSSYSDLSYATLHLYLRGWDWI 377
            |.|:::.|:|..|......:|..:..||          |.|...|...||::|.|.|.|..
Human    39 SPLAYMLSLYRDPLPRADIIRSLQAEDVAVDGQNWTFAFDFSFLSQQEDLAWAELRLQLSS---- 99

  Fly   378 SAHQP---GLLEEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFR-----HSIPSGLGQWV- 433
            ....|   .|..||..||:.|........:.......|...:....|.     ..:...|.:|:
Human   100 PVDLPTEGSLAIEIFHQPKPDTEQASDSCLERFQMDLFTVTLSQVTFSLGSMVLEVTRPLSKWLK 164

  Fly   434 ---AVDLK------------------SLLGNLGSNMTQE--------ILIKGAETWMKSLVVTTD 469
               |::.:                  ::|..|.||::||        :|.:...:|
Human   165 HPGALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQRQLGGSTLLWEAESSW--------- 220

  Fly   470 NTSKNPLTVHIEIGSQKKHRRKRSVYMDCTENDHDMRCCRYPLKVNFTSFGW-HFVVAPTSFDAY 533
            ...:..|:  .|.|  |:|||...       .|....|.:...:|:|...|| .:::.|..::||
Human   221 RAQEGQLS--WEWG--KRHRRHHL-------PDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAY 274

  Fly   534 FCSGDC--KVGYLEQYP--HTHLAALTTSATP------CCSPTKMSSLSLLYFDDNHNLVLSVIP 588
            .|.|:|  .||. |.:|  |.::.:|.....|      ||:|.|...||:||. ||..::|....
Human   275 RCEGECPNPVGE-EFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYV-DNGRVLLDHHK 337

  Fly   589 NMSVEGCSC 597
            :|.||.|.|
Human   338 DMIVEECGC 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	33/101 (33%)
NODAL	NP_060525.3	TGFb_propeptide	29..166	CDD:279078	28/130 (22%)
		TGFB	247..346	CDD:214556	33/100 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160047
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840