Protein Alignment myo and gbb

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 103/534 - (19%)
• Similarity: 200/534 - (37%)
• Gaps: 151/534 - (28%)

  Fly   131 KNGSSSISADDKINENMGIFQMKVQSKPGKKSTPLAKVSEHGDLSRVQSVSLYRNTLINIESMLQ 195
            :|.|.:::....:...|.:......:.|..::|......::|                ..::::.
  Fly     5 RNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNG----------------KDQTIMH 53

  Fly   196 RQLREKAKVDSIESIKMHILMRLNLKKLP------NITKPISVPQNIIDNFYRDYNASSKTTVWN 254
            |.|.|..|:|    :...||..|.:.:.|      .::...|.|:.::|.::| ..|....:..:
  Fly    54 RVLSEDDKLD----VSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHR-ITAEEGLSDQD 113

  Fly   255 RMESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDE 319
            ..:..:..|.|                ..|:.::.|:......|:.||:|....:|||.:...::
  Fly   114 EDDDYERGHRS----------------RRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNK 162

  Fly   320 EYESI--LSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSD--LSYATLHLYLRGWD--WIS 378
            .:.::  |.|               .|.|::   .|.:.:..:|  |..|.|.:|....:  |::
  Fly   163 RHHNVDELRH---------------EHGRRL---WFDVSNVPNDNYLVMAELRIYQNANEGKWLT 209

  Fly   379 AHQ----------PGLLEEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWV 433
            |::          .|.|.:...:|...:           |||  ...|...|.  ::..||.:|:
  Fly   210 ANREFTITVYAIGTGTLGQHTMEPLSSV-----------NTT--GDYVGWLEL--NVTEGLHEWL 259

  Fly   434 --------------AV---DLKSLLGNLG------SNMTQEILI---KGAETWMKSLVVTTDNTS 472
                          ||   |.:..|.::|      .:..|..:|   :|.|. :|:...::.:.|
  Fly   260 VKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPEL-IKATAHSSHHRS 323

  Fly   473 KNPLTVHIEIGSQKKHRRKRSVY---------MDCTENDHDMRCCRYPLKVNFTSFGWH-FVVAP 527
            |.        .:....:||:||.         |:.|.:     |....|.::|...||| :::||
  Fly   324 KR--------SASHPRKRKKSVSPNNVPLLEPMESTRS-----CQMQTLYIDFKDLGWHDWIIAP 375

  Fly   528 TSFDAYFCSGDCKV---GYLEQYPH------THLAALTTSATPCCSPTKMSSLSLLYFDDNHNLV 583
            ..:.|::|||:|..   .::....|      .||........|||:||::.:|.:||..::.|:.
  Fly   376 EGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVN 440

  Fly   584 LSVIPNMSVEGCSC 597
            |....||.|:.|.|
  Fly   441 LKKYRNMIVKSCGC 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	30/100 (30%)
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	56/329 (17%)
		TGF_beta_BMP5_like	353..455	CDD:381639	31/107 (29%)