Protein Alignment myo and INHBB

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_002184.2
• Gene: INHBB / 3625
• HGNCID: 6067
• Length: 407
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 103/439 - (23%)
• Similarity: 165/439 - (37%)
• Gaps: 129/439 - (29%)

  Fly   196 RQLREKAKVDS--IESIKMHILMRLNLKKLPNITKPISVPQNIIDNFYRDYNASSKTTVWNRMES 258
            |:..|..:||.  :|::|.|||.||.::..||||.  :||:..:....|..:| .|.....|:|.
Human    62 RRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITH--AVPKAAMVTALRKLHA-GKVREDGRVEI 123

  Fly   259 IDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEEYES 323
               .||..:.:.|                 .|....|:|.:                 :..|.:.
Human   124 ---PHLDGHASPG-----------------ADGQERVSEII-----------------SFAETDG 151

  Fly   324 ILSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLLEEI 388
            :.|....:|.|       :.:....::|..|          |:|.|||:...::          :
Human   152 LASSRVRLYFF-------ISNEGNQNLFVVQ----------ASLWLYLKLLPYV----------L 189

  Fly   389 KKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLGNLG------SN 447
            :|..|        |.:||        ||...|..|.     .:|..|:.:..|...|      :.
Human   190 EKGSR--------RKVRV--------KVYFQEQGHG-----DRWNMVEKRVDLKRSGWHTFPLTE 233

  Fly   448 MTQEILIKG-------------AETWMKSLVVTTDNTSKNP-LTVHIEIGSQKKHRRKRSVYMDC 498
            ..|.:..:|             .|..:..:.|.....|..| :.|...:|..:...|||.:..|.
Human   234 AIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDG 298

  Fly   499 TENDHDMRCCRYPLKVNFTSFGWH-FVVAPTSFDAYFCSGDCKVGYLEQYPHT----HLAALTT- 557
            ..|    .|||....::|...||: :::|||.:...:|.|.|. .||...|.:    |.|.:..
Human   299 RTN----LCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCP-AYLAGVPGSASSFHTAVVNQY 358

  Fly   558 --------SATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
                    :...||.|||:|::|:|||||.:|:|...:|||.||.|.|:
Human   359 RMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	37/104 (36%)
INHBB	NP_002184.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..62		103/439 (23%)
		TGFb_propeptide	57..278	CDD:279078	58/303 (19%)
		TGFB	303..406	CDD:214556	37/103 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010